Mechanical Thrombectomy Quality Indicators Study in Czech Stroke Centers: Results of the METRICS Study.


Journal

Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
ISSN: 1532-8511
Titre abrégé: J Stroke Cerebrovasc Dis
Pays: United States
ID NLM: 9111633

Informations de publication

Date de publication:
Apr 2022
Historique:
received: 11 10 2021
revised: 03 01 2022
accepted: 04 01 2022
pubmed: 2 2 2022
medline: 25 3 2022
entrez: 1 2 2022
Statut: ppublish

Résumé

Rigorous and regular evaluation of defined quality indicators is crucial for further improvement of both technical and clinical results after mechanical thrombectomy (MT) for acute ischemic stroke (AIS). Following the recent international multi-society consensus quality indicators, we aimed to assess trend in these indicators on national level. The prospective multicenter study (METRICS) was conducted in Czech Republic (CR) in year 2019. All participating centers collected technical and clinical data including defined quality indicators and results were subsequently compared with those from year 2016. In the 2019, 1375 MT were performed in the CR and 1178 (86%) patients (50.3% males, mean age 70.5 ± 13.0 years) were analyzed. Recanalization (TICI 2b-3) was achieved in 83.7% of patients and 46.2% of patients had good 3-month clinical outcome. Following time intervals were shortened in comparison to 2016: "hospital arrival - GP" (77 vs. 53 min; p<0.0001), "hospital arrival - maximal achieved recanalization" (122 vs. 93 min; p<0.0001), and "stroke onset - maximal achieved recanalization" (240 vs. 229 min; p p<0.0001). More patients with tandem occlusion were treated in 2019 (7.8 vs. 16.5%; p<0.0001) and more secondary transports were in 2019 (31.3 vs. 37.8%; p=0.002). No difference was found in 3-month clinical outcome and in the rate of periprocedural complications. Results of the METRICS study met all criteria of multi-society consensus quality indicators. Nationwide comparison between 2016 and 2019 showed improvement in the key time intervals, but without better overall clinical outcomes after MT.

Sections du résumé

BACKGROUND AND PURPOSE OBJECTIVE
Rigorous and regular evaluation of defined quality indicators is crucial for further improvement of both technical and clinical results after mechanical thrombectomy (MT) for acute ischemic stroke (AIS). Following the recent international multi-society consensus quality indicators, we aimed to assess trend in these indicators on national level.
MATERIAL AND METHODS METHODS
The prospective multicenter study (METRICS) was conducted in Czech Republic (CR) in year 2019. All participating centers collected technical and clinical data including defined quality indicators and results were subsequently compared with those from year 2016.
RESULTS RESULTS
In the 2019, 1375 MT were performed in the CR and 1178 (86%) patients (50.3% males, mean age 70.5 ± 13.0 years) were analyzed. Recanalization (TICI 2b-3) was achieved in 83.7% of patients and 46.2% of patients had good 3-month clinical outcome. Following time intervals were shortened in comparison to 2016: "hospital arrival - GP" (77 vs. 53 min; p<0.0001), "hospital arrival - maximal achieved recanalization" (122 vs. 93 min; p<0.0001), and "stroke onset - maximal achieved recanalization" (240 vs. 229 min; p p<0.0001). More patients with tandem occlusion were treated in 2019 (7.8 vs. 16.5%; p<0.0001) and more secondary transports were in 2019 (31.3 vs. 37.8%; p=0.002). No difference was found in 3-month clinical outcome and in the rate of periprocedural complications. Results of the METRICS study met all criteria of multi-society consensus quality indicators.
CONCLUSION CONCLUSIONS
Nationwide comparison between 2016 and 2019 showed improvement in the key time intervals, but without better overall clinical outcomes after MT.

Identifiants

pubmed: 35104746
pii: S1052-3057(22)00005-2
doi: 10.1016/j.jstrokecerebrovasdis.2022.106308
pii:
doi:

Types de publication

Journal Article Multicenter Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

106308

Informations de copyright

Copyright © 2022 Elsevier Inc. All rights reserved.

Déclaration de conflit d'intérêts

Conflict of Interest The authors declare that they have no conflict of interest.

Auteurs

Martin Köcher (M)

Department of Radiology and Neurology, Palacký University Faculty of Medicine and University Hospital Olomouc, Czech Republic.

Daniel Šaňák (D)

Department of Radiology and Neurology, Palacký University Faculty of Medicine and University Hospital Olomouc, Czech Republic. Electronic address: daniel.sanak@centrum.cz.

Jana Zapletalová (J)

Department of Medical Biophysics and Statistics, Palacký University Faculty of Medicine Olomouc, Czech Republic.

Filip Cihlář (F)

Department of Radiology and Neurology, Masaryk's Hospital Faculty of Health Studies, J.E. Purkinje University, KZ a.s., Ústí nad Labem, Czech Republic.

Daniel Czerny (D)

Department of Radiology and Neurology, University of Ostrava Faculty of Medicine and University Hospital, Ostrava, Czech Republic.

David Černík (D)

Department of Radiology and Neurology, University of Ostrava Faculty of Medicine and University Hospital, Ostrava, Czech Republic.

Petr Duras (P)

Department of Radiology and Neurology, Charles University Faculty of Medicine and University Hospital Plzen, Czech Republic.

Jan Fiksa (J)

Department of Neurology and 2nd Department of Internal Medicine, Charles University 1st Faculty of Medicine and General University Hospital Prague, Czech Republic.

Jakub Hustý (J)

Department of Neurology and Radiology, Hospital Na Homolce Prague, Czech Republic.

Lubomír Jurák (L)

Department of Neurology and Radiology, Hospital Liberec, Czech Republic.

Martin Kovář (M)

Department of Neurology and Radiology, Hospital Na Homolce Prague, Czech Republic.

Jiří Lacman (J)

Department of Radiology and Neurology, Central Military University Hospital Prague, Czech Republic.

Radek Pádr (R)

Department of Radiology and Neurology, Charles University 2nd Faculty of Medicine and University Hospital Motol Prague, Czech Republic.

Pavel Procházka (P)

Department of Neurology and 2nd Department of Internal Medicine, Charles University 1st Faculty of Medicine and General University Hospital Prague, Czech Republic.

Jan Raupach (J)

Department of Radiology and Neurology, Charles University Faculty of Medicine and University Hospital, Hradec Králové, Czech Republic.

Martin Reiser (M)

Department of Neurology and Radiology, Hospital České Budějovice, Czech Republic.

Vladimír Rohan (V)

Department of Radiology and Neurology, Masaryk University Faculty of Medicine, University Hospital Brno, Czech Republic.

Martin Roubec (M)

Department of Radiology and Neurology, Charles University Faculty of Medicine and University Hospital Plzen, Czech Republic.

Jindřich Sova (J)

Department of Neurology and Radiology, Hospital České Budějovice, Czech Republic.

Miroslav Šercl (M)

Department of Neurology and Radiology, Hospital Liberec, Czech Republic.

Miroslav Škorňa (M)

Department of Radiology and Neurology, Masaryk University Faculty of Medicine, University Hospital Brno, Czech Republic.

Libor Šimůnek (L)

Department of Radiology and Neurology, Charles University Faculty of Medicine and University Hospital, Hradec Králové, Czech Republic.

Alena Šnajdrová (A)

Department of Neurology and Radiology, Hospital Na Homolce Prague, Czech Republic.

Martin Šrámek (M)

Department of Radiology and Neurology, Central Military University Hospital Prague, Czech Republic.

Aleš Tomek (A)

Department of Radiology and Neurology, Charles University 2nd Faculty of Medicine and University Hospital Motol Prague, Czech Republic.

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