Temporal shifts in HIV-related risk factors among cohorts of adolescent girls and young women enrolled in DREAMS programming: evidence from Kenya, Malawi and Zambia.


Journal

BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874

Informations de publication

Date de publication:
01 02 2022
Historique:
entrez: 2 2 2022
pubmed: 3 2 2022
medline: 23 3 2022
Statut: epublish

Résumé

To assess temporal shifts in HIV risk factors among adolescent girls (AG, aged 15-19 years) and young women (YW, aged 20-24 years) in Kenya, Malawi and Zambia. Prospective cohorts with two time points (Kenya: 2016/2017, 2018; Malawi: 2017, 2018; Zambia: 2016/2017, 2018) SETTING: Community-based programming. 1247 AG (Kenya: 389, Malawi: 371, Zambia: 487) and 1628 YW (Kenya: 347, Malawi: 883, Zambia: 398) INTERVENTION: Determined, Resilient, Empowered, AIDS-free, Mentored and Safe (DREAMS), a multisectoral approach to reduce AGYW's HIV vulnerability by delivering a package of tailored, multilayered activities and services.Primary and secondary outcome measures: HIV testing, sexually transmitted infection (STI) symptom experience, number of sexual partners, condom use (consistently, at last sex), transactional sex, experience of physical violence (from intimate partners) and sexual violence (from intimate partners and strangers/non-partners). Changes in HIV-related risk behaviours among DREAMS participants varied by age group and country. Among AG, HIV testing increased (Kenya and Zambia) and sexual violence from partners (in Kenya and Malawi) and non-partners (in Malawi) decreased. Among YW, HIV testing increased and STI experience decreased in Malawi; consistent condom use decreased in Kenya; transactional sex increased in Kenya and Zambia; and physical violence (in Malawi) and sexual violence from partners (in Kenya and Malawi) and non-partners (all three countries) decreased over time. Improvements in HIV testing and reductions in experiences of sexual violence were coupled with variable shifts in HIV-related risk behaviours among DREAMS participants in Kenya, Malawi and Zambia. Additional consideration of AGYW's risk circumstances during key life transitions may be needed to address the risk heterogeneity among AG and YW across different contexts.

Identifiants

pubmed: 35105561
pii: bmjopen-2020-047843
doi: 10.1136/bmjopen-2020-047843
pmc: PMC8808410
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

e047843

Informations de copyright

© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: NP works full-time for ViiV Healthcare. ViiV Healthcare did not fund the study. The contents of the manuscript do not reflect the views of ViiV Healthcare. SM, CJH, SKP, JO, EC, VM, WC, MM, BM and JP declare no conflicts of interest.

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Auteurs

Sanyukta Mathur (S)

Population Council, Washington, District of Columbia, USA smathur@popcouncil.org.

Craig J Heck (CJ)

Population Council, New York, New York, USA.

Sangram Kishor Patel (S)

Population Council India, New Delhi, Delhi, India.

Jerry Okal (J)

Population Council Kenya, Nairobi, Kenya.

Effie Chipeta (E)

Centre for Reproductive Health, University of Malawi College of Medicine, Blantyre, Southern Region, Malawi.

Victor Mwapasa (V)

Centre for Reproductive Health, University of Malawi College of Medicine, Blantyre, Southern Region, Malawi.

Wanangwa Chimwaza (W)

Centre for Reproductive Health, University of Malawi College of Medicine, Blantyre, Southern Region, Malawi.

Maurice Musheke (M)

Independent Consultant, Lusaka, Zambia.

Bidhubhusan Mahapatra (B)

Population Council India, New Delhi, Delhi, India.

Julie Pulerwitz (J)

Population Council, Washington, District of Columbia, USA.

Nanlesta Pilgrim (N)

ViiV Healthcare US, Research Triangle Park, North Carolina, USA.

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