What treatments work for anxiety and depression in children and adolescents with chronic fatigue syndrome? An updated systematic review.
anxiety disorders
child & adolescent psychiatry
depression & mood disorders
mental health
paediatrics
Journal
BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874
Informations de publication
Date de publication:
31 01 2022
31 01 2022
Historique:
entrez:
2
2
2022
pubmed:
3
2
2022
medline:
16
3
2022
Statut:
epublish
Résumé
Children with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) experience a higher prevalence of depression and anxiety compared with age-matched controls. Our previous systematic reviews in 2015/16 found little evidence for effective treatment for children with CFS/ME with comorbid depression and/or anxiety. This review updates these findings. A systematic review. We searched Cochrane library, Medline, Embase and PsycINFO databases from 2015 to 2020. We combined the updated results with our previous reviews in a narrative synthesis. Inclusion criteria: <18 years old; diagnosed with CFS/ME (using Centers for Disease Control and Prevention, National Institute for Health and Care Excellence or Oxford criteria); validated measures of depression and/or anxiety. Observational studies or randomised controlled trials. Any or none. Studies with outcome measures of anxiety, depression or fatigue. The updated review identified two studies. This brings the total number of paediatric CFS/ME studies with a measure of anxiety and/or depression since 1991 to 16. None of the studies specifically targeted depression, nor anxiety. One new study showed the Lightning Process (in addition to specialist care) was more effective at reducing depressive and anxiety symptoms compared with specialist care alone. Previous studies evaluated cognitive-behavioural therapy (CBT); pharmacological interventions and behavioural approaches. CBT-type interventions had most evidence for improving comorbid anxiety and/or depressive symptoms but varied in delivery and modality. Other interventions showed promise but studies were small and have not been replicated. Very few paediatric CFS/ME intervention studies have been conducted. This review update does not significantly add to what is known from previous reviews. The evidence is of poor quality and insufficient to conclude which interventions are effective at treating comorbid anxiety and/or depression in paediatric CFS/ME. CRD42016043488 and CRD42015016813.
Identifiants
pubmed: 35105619
pii: bmjopen-2021-051358
doi: 10.1136/bmjopen-2021-051358
pmc: PMC8808375
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
e051358Informations de copyright
© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: EC acts as a non-paid medical advisor for the Sussex and Kent ME society.
Références
J Psychosom Res. 2014 Nov;77(5):409-14
pubmed: 25260861
PLoS Med. 2009 Jul 21;6(7):e1000097
pubmed: 19621072
Clin Child Psychol Psychiatry. 2019 Jul;24(3):580-592
pubmed: 30945566
Clin Rehabil. 2010 Dec;24(12):1072-9
pubmed: 20605858
J Affect Disord. 2016 Jan 15;190:333-340
pubmed: 26544617
An Pediatr (Barc). 2007 Jul;67(1):74-7
pubmed: 17663911
BMJ. 2019 Aug 28;366:l4898
pubmed: 31462531
J Am Acad Child Adolesc Psychiatry. 1997 Apr;36(4):554-65
pubmed: 9100431
Adv Mind Body Med. 2014 Winter;28(1):4-14
pubmed: 24445302
BMJ Open. 2017 Sep 5;7(9):e015481
pubmed: 28877941
Arch Dis Child. 2013 Jun;98(6):425-8
pubmed: 23619200
J Pediatr. 2017 Apr;183:184-190
pubmed: 28088398
Arch Dis Child. 2005 Apr;90(4):369-72
pubmed: 15781925
BMJ. 2020 Jan 16;368:l6890
pubmed: 31948937
J Child Psychol Psychiatry. 2000 Jul;41(5):645-55
pubmed: 10946756
J Consult Clin Psychol. 1984 Dec;52(6):955-67
pubmed: 6520288
Eur Child Adolesc Psychiatry. 2021 Nov;30(11):1733-1743
pubmed: 32964335
J Child Psychol Psychiatry. 1987 Jan;28(1):43-60
pubmed: 3558538
J Paediatr Child Health. 2009 May;45(5):286-90
pubmed: 19493121
J Transl Med. 2020 Feb 24;18(1):100
pubmed: 32093722
Pediatrics. 2013 Jun;131(6):e1788-95
pubmed: 23669515
Front Pediatr. 2019 Feb 21;7:21
pubmed: 30847333
Arch Gen Psychiatry. 1965 Jan;12:63-70
pubmed: 14221692
J Psychosom Res. 2007 Oct;63(4):377-80
pubmed: 17905045
J Anxiety Disord. 2003;17(6):605-25
pubmed: 14624814
Arch Dis Child. 2018 Feb;103(2):155-164
pubmed: 28931531
Arch Dis Child. 2009 Oct;94(10):752-6
pubmed: 19001477
Lancet. 2012 Apr 14;379(9824):1412-8
pubmed: 22385683
BMC Psychiatry. 2020 Sep 21;20(1):457
pubmed: 32957944
Br J Health Psychol. 2013 Sep;18(3):508-25
pubmed: 22989369
Br J Psychiatry. 1999 Nov;175:452-4
pubmed: 10789277
Clin Pediatr (Phila). 2017 Jan;56(1):85-89
pubmed: 27421749
Arch Dis Child. 2002 Feb;86(2):95-7
pubmed: 11827901
Ann Intern Med. 1994 Dec 15;121(12):953-9
pubmed: 7978722
Acta Psychiatr Scand. 1983 Jun;67(6):361-70
pubmed: 6880820
J Psychiatr Res. 1997 Jan-Feb;31(1):133-47
pubmed: 9201655
Clin Child Psychol Psychiatry. 2018 Jul;23(3):398-408
pubmed: 29096528
PLoS One. 2015 Jul 06;10(7):e0132421
pubmed: 26147503
BMJ. 2016 Oct 12;355:i4919
pubmed: 27733354
Brain Dev. 2011 Nov;33(10):832-41
pubmed: 21530119
Behav Res Ther. 2012 May;50(5):304-12
pubmed: 22459729
J R Soc Med. 1991 Feb;84(2):118-21
pubmed: 1999813
BMJ Open. 2016 Oct 11;6(10):e012271
pubmed: 27729349
Pediatrics. 2007 Mar;119(3):e603-9
pubmed: 17332180