Comparative in vitro activity of piperacillin-tazobactam and temocillin against third-generation cephalosporin-resistant, carbapenem-susceptible Escherichia coli and Klebsiella pneumoniae.

CTX-M ESBL Enterobacteriaceae Germany

Journal

GMS infectious diseases
ISSN: 2195-8831
Titre abrégé: GMS Infect Dis
Pays: Germany
ID NLM: 101694381

Informations de publication

Date de publication:
2021
Historique:
entrez: 2 2 2022
pubmed: 3 2 2022
medline: 3 2 2022
Statut: epublish

Résumé

Carbapenems are considered the drugs of choice for first-line treatment of severe infections caused by carbapenem-susceptible, extended-spectrum β-lactamases (ESBL)-producing Enterobacterales, while piperacillin-tazobactam has been recommended as an alternative for treatment of non-severe infections. Temocillin is stable to ESBL and AmpC enzymes and may thus represent another treatment option. This study assessed the in vitro activity of piperacillin-tazobactam and temocillin against third-generation cephalosporin (3GC)-resistant

Identifiants

pubmed: 35106270
doi: 10.3205/id000077
pii: id000077
pmc: PMC8777484
doi:

Banques de données

Dryad
['10.5061/dryad.931zcrjkc']

Types de publication

Journal Article

Langues

eng

Pagination

Doc08

Informations de copyright

Copyright © 2021 Kresken et al.

Déclaration de conflit d'intérêts

MK is a partner and CEO of Antiinfectives Intelligence GmbH, a research organization providing services to pharmaceutical companies. YP and GW declare that they have no competing interests.

Références

Int J Antimicrob Agents. 2021 Jan;57(1):106223
pubmed: 33166691
Int J Antimicrob Agents. 2018 Jul;52(1):100-103
pubmed: 29580930
Clin Microbiol Rev. 2009 Jan;22(1):161-82, Table of Contents
pubmed: 19136439
Clin Microbiol Rev. 2005 Oct;18(4):657-86
pubmed: 16223952
Clin Microbiol Infect. 2019 Aug;25(8):932-942
pubmed: 30986558
J Antimicrob Chemother. 2015 Mar;70(3):891-8
pubmed: 25433006
Eur J Clin Microbiol Infect Dis. 2020 Jun;39(6):1185-1191
pubmed: 32096107
GMS Infect Dis. 2021 Dec 21;9:Doc08
pubmed: 35106270
Clin Microbiol Rev. 2018 Feb 14;31(2):
pubmed: 29444952
Lancet Infect Dis. 2013 Sep;13(9):785-96
pubmed: 23969216
Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):E3463-E3470
pubmed: 29581252
J Antimicrob Chemother. 2011 Jan;66(1):37-47
pubmed: 21036771

Auteurs

Michael Kresken (M)

Antiinfectives Intelligence GmbH, Cologne, Germany.
Rheinische Fachhochschule Köln gGmbH, Cologne, Germany.

Yvonne Pfeifer (Y)

Robert Koch Institute, FG13 Nosocomial Pathogens and Antibiotic Resistance, Wernigerode, Germany.

Guido Werner (G)

Robert Koch Institute, FG13 Nosocomial Pathogens and Antibiotic Resistance, Wernigerode, Germany.

Classifications MeSH