Subclinical Hypertrophic Cardiomyopathy in Elite Athletes: Knowledge Gaps Persist.
ACTC1, actin alpha cardiac muscle 1
CMR, cardiac magnetic resonance
EF, ejection fraction
HCM, hypertrophic cardiomyopathy
LGE, late gadolinium enhancement
LV, left ventricle
LVH, left ventricular hypertrophy
RV, right ventricle
cardiac magnetic resonance
cardiomyopathy
genetics
Journal
JACC. Case reports
ISSN: 2666-0849
Titre abrégé: JACC Case Rep
Pays: Netherlands
ID NLM: 101757292
Informations de publication
Date de publication:
19 Jan 2022
19 Jan 2022
Historique:
received:
28
07
2021
revised:
07
10
2021
accepted:
04
11
2021
entrez:
2
2
2022
pubmed:
3
2
2022
medline:
3
2
2022
Statut:
epublish
Résumé
Subclinical hypertrophic cardiomyopathy (HCM) is a phenotypic entity that has emerged from the increased use of cardiovascular magnetic resonance imaging in the evaluation and family screening of patients with HCM. We describe the case of a competitive athlete with a sarcomere gene mutation and family history of HCM who was found to exhibit the subclinical HCM phenotype on cardiovascular magnetic resonance imaging in the absence of left ventricular hypertrophy. We discuss the clinical uncertainties in her management. (
Identifiants
pubmed: 35106492
doi: 10.1016/j.jaccas.2021.11.004
pii: S2666-0849(21)01003-2
pmc: PMC8784716
doi:
Types de publication
Case Reports
Langues
eng
Pagination
94-98Subventions
Organisme : British Heart Foundation
ID : FS/CRTF/21/24143
Pays : United Kingdom
Informations de copyright
© 2022 The Authors.
Déclaration de conflit d'intérêts
Dr Chan is supported by a British Heart Foundation (BHF) Clinical Research Training Fellowship FS/CRTF/21/24143. Dr Monserrat is the CEO of Health in Code, a genetic sequencing enterprise. Dr Captur is supported by BHF Special Programme Grant SP/20/2/34841 (MyoFit46). All other authors have reported that they have no relationships relevant to the contents of this paper to disclose.
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