Characterization in nonhuman primates of (R)-[


Journal

European journal of nuclear medicine and molecular imaging
ISSN: 1619-7089
Titre abrégé: Eur J Nucl Med Mol Imaging
Pays: Germany
ID NLM: 101140988

Informations de publication

Date de publication:
06 2022
Historique:
received: 11 11 2021
accepted: 19 01 2022
pubmed: 3 2 2022
medline: 26 5 2022
entrez: 2 2 2022
Statut: ppublish

Résumé

GluN2B containing N-methyl-D-aspartate receptors (NMDARs) play an essential role in neurotransmission and are a potential treatment target for multiple neurological and neurodegenerative diseases, including stroke, Alzheimer's disease, and Parkinson's disease. (R)-[ The radiosynthesis of (R)-[ (R)- and (S)-[ In rhesus monkeys, (R)-[

Identifiants

pubmed: 35107627
doi: 10.1007/s00259-022-05698-9
pii: 10.1007/s00259-022-05698-9
pmc: PMC9165293
doi:

Substances chimiques

Radiopharmaceuticals 0
Receptors, N-Methyl-D-Aspartate 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2153-2162

Subventions

Organisme : NIMH NIH HHS
ID : U01 MH107803
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001863
Pays : United States

Informations de copyright

© 2022. The Author(s).

Références

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Auteurs

MingQiang Zheng (M)

PET Center, Yale University, New Haven, CT, USA.

Hazem Ahmed (H)

PET Center, Yale University, New Haven, CT, USA.
Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland.

Kelly Smart (K)

PET Center, Yale University, New Haven, CT, USA.

Yuping Xu (Y)

PET Center, Yale University, New Haven, CT, USA.
Jiangsu Institute of Nuclear Medicine, Wuxi, Jiangsu, China.

Daniel Holden (D)

PET Center, Yale University, New Haven, CT, USA.

Michael Kapinos (M)

PET Center, Yale University, New Haven, CT, USA.

Zachary Felchner (Z)

PET Center, Yale University, New Haven, CT, USA.

Ahmed Haider (A)

Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland.

Gilles Tamagnan (G)

PET Center, Yale University, New Haven, CT, USA.

Richard E Carson (RE)

PET Center, Yale University, New Haven, CT, USA.

Yiyun Huang (Y)

PET Center, Yale University, New Haven, CT, USA. henry.huang@yale.edu.

Simon M Ametamey (SM)

Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland. simon.ametamey@pharma.ethz.ch.

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Classifications MeSH