Seroepidemiologic evidence of Q fever and associated factors among workers in veterinary service laboratory in South Korea.
Journal
PLoS neglected tropical diseases
ISSN: 1935-2735
Titre abrégé: PLoS Negl Trop Dis
Pays: United States
ID NLM: 101291488
Informations de publication
Date de publication:
Feb 2022
Feb 2022
Historique:
received:
18
05
2021
accepted:
03
12
2021
entrez:
2
2
2022
pubmed:
3
2
2022
medline:
11
2
2022
Statut:
epublish
Résumé
The incidence of Q fever has rapidly increased in South Korea since 2015. This study was undertaken to investigate the seroprevalence and seroreactivity of Q fever and the risk factors associated with its seroprevalence among workers in the veterinary service laboratory (VSL) in South Korea. This seroepidemiologic study was conducted in a total of 661 human subjects out of 1,328 subjects working in 50 VSL existing in South Korea between July 15 and July 29, 2019. Data were collected by administering survey questionnaires and by analyzing collected blood samples to determine the presence of antibodies against Coxiella burnetii. The seroprevalence and seroreactivity of C. burnetii infection were determined based on serum titers as (phase II IgG ≥1:256 and/or IgM ≥1:16) and (phase II IgG ≥1:16 and/or IgM ≥1:16) as determined by indirect immunofluorescent assay. Work, work environment, behavioral risk and protective factors associated with seroprevalence of Q fever were assessed by employing multivariable logistic regression analysis. Among the 661, the seroprevalence and seroreactivity of C. burnetii infection were 7.9% and 16.0%, respectively. Multivariate logistic regression analysis showed the risk factors significantly associated with seroprevalence were the antemortem inspection of cattle, goats, or sheep (APR (adjusted prevalence ratio), 2.52; 95% CI, 1.23-4.70)), animal blood splashed into or around eyes (APR, 2.24; 95% CI, 1.04-4.41), and contact with animals having Q fever (APR, 6.58; 95% CI, 3.39-10.85) during the previous year. This study suggests the need for precautions when contact with cattle, goats, or sheep is expected, especially during the antemortem inspection, when dealing with C. burnetii infected animals, or when there is a risk of ocular contact with animal derivatives. Therefore, we recommend the consistent use of appropriate personal protective equipment and other protective measures including PPE treatment and washing of body surfaces after work to prevent C. burnetii infections among VSL staff in South Korea.
Identifiants
pubmed: 35108271
doi: 10.1371/journal.pntd.0010054
pii: PNTD-D-21-00722
pmc: PMC8809587
doi:
Substances chimiques
Antibodies, Bacterial
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0010054Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
PLoS One. 2014 Sep 26;9(9):e108674
pubmed: 25259959
Lancet Infect Dis. 2002 Nov;2(11):686-91
pubmed: 12409049
Epidemiol Infect. 2017 Jul;145(9):1834-1842
pubmed: 28434420
MMWR Recomm Rep. 2013 Mar 29;62(RR-03):1-30
pubmed: 23535757
JAMA Netw Open. 2018 Aug 3;1(4):e181580
pubmed: 30646123
Sci Rep. 2019 Dec 2;9(1):18132
pubmed: 31792307
Aust N Z J Public Health. 2001 Aug;25(4):362-7
pubmed: 11529620
Int J Environ Res Public Health. 2018 Oct 16;15(10):
pubmed: 30332766
Epidemics. 2015 Dec;13:37-43
pubmed: 26616040
J Dairy Sci. 2007 Dec;90(12):5352-60
pubmed: 18024725
Emerg Infect Dis. 2004 Jul;10(7):1282-9
pubmed: 15324550
Emerg Infect Dis. 2005 Apr;11(4):619-21
pubmed: 15829205
PLoS One. 2015 Sep 23;10(9):e0138817
pubmed: 26398249
PLoS One. 2016 Jan 05;11(1):e0144953
pubmed: 26731333
Emerg Infect Dis. 2004 Jul;10(7):1264-9
pubmed: 15324547
PLoS Negl Trop Dis. 2013 Jul 18;7(7):e2324
pubmed: 23875053
Clin Infect Dis. 1995 Mar;20(3):489-95; quiz 496
pubmed: 7756465
BMC Infect Dis. 2019 Oct 28;19(1):903
pubmed: 31660875
Aust N Z J Public Health. 2018 Oct;42(5):451-455
pubmed: 29644762
Yonsei Med J. 2017 Jan;58(1):259-260
pubmed: 27873523
J Prev Med Public Health. 2009 Jul;42(4):237-42
pubmed: 19675400
Vet Res. 2006 Nov-Dec;37(6):827-33
pubmed: 16973121
N Engl J Med. 1994 Feb 3;330(5):371
pubmed: 8277971
J Prev Med Public Health. 2017;50(3):195-200
pubmed: 28605884
Int J Occup Med Environ Health. 2015;28(5):901-7
pubmed: 26224501
Am J Epidemiol. 1999 Jul 1;150(1):67-74
pubmed: 10400556
Acta Vet Scand. 2013 Feb 18;55:13
pubmed: 23419216
Transbound Emerg Dis. 2017 Jun;64(3):959-966
pubmed: 26749554
Vet Microbiol. 2015 Dec 14;181(1-2):119-29
pubmed: 26315774
Lancet. 2006 Feb 25;367(9511):679-88
pubmed: 16503466
Vet Microbiol. 2011 May 5;149(3-4):298-306
pubmed: 21146331
Euro Surveill. 2010 Mar 25;15(12):
pubmed: 20350500
PLoS One. 2015 Jul 10;10(7):e0131848
pubmed: 26161658
Microorganisms. 2019 Nov 29;7(12):
pubmed: 31795442
Vet Microbiol. 2014 Sep 17;173(1-2):152-5
pubmed: 25061007
Iran Red Crescent Med J. 2014 Sep 05;16(9):e15308
pubmed: 25593722
Vet Rec. 2000 Jan 29;146(5):131-6
pubmed: 10706331
Clin Microbiol Rev. 2017 Jan;30(1):115-190
pubmed: 27856520
Vet Microbiol. 2010 Jan 27;140(3-4):297-309
pubmed: 19875249
Vector Borne Zoonotic Dis. 2012 Jul;12(7):552-7
pubmed: 22607080
Vaccine. 2009 Mar 23;27(14):2037-41
pubmed: 19428827
Clin Microbiol Rev. 1999 Oct;12(4):518-53
pubmed: 10515901
J Infect Public Health. 2020 Apr;13(4):544-551
pubmed: 31706842
Euro Surveill. 2013 Jul 11;18(28):
pubmed: 23870098
Vector Borne Zoonotic Dis. 2002 Fall;2(3):179-91
pubmed: 12737547
PLoS One. 2019 Feb 19;14(2):e0211781
pubmed: 30779802
Pathogens. 2019 Apr 16;8(2):
pubmed: 30995815
Biomed Res Int. 2016;2016:7059196
pubmed: 26966688
J Korean Med Sci. 2018 Aug 16;33(39):e245
pubmed: 30250410
Ann N Y Acad Sci. 2009 May;1166:90-3
pubmed: 19538267
Clin Infect Dis. 2009 Mar 1;48(5):550-7
pubmed: 19191638