Effect of pancrelipase in preventing pancreatic dysfunction after pancreaticoduodenectomy.
Nutrition assessment
Pancreatectomy
Pancreaticoduodenectomy
Pancrelipase
Journal
Fujita medical journal
ISSN: 2189-7255
Titre abrégé: Fujita Med J
Pays: Japan
ID NLM: 101745077
Informations de publication
Date de publication:
2019
2019
Historique:
received:
15
10
2018
accepted:
28
10
2018
entrez:
3
2
2022
pubmed:
1
1
2019
medline:
1
1
2019
Statut:
ppublish
Résumé
Patients who have undergone pancreaticoduodenectomy (PD) may experience a long-term decrease in quality of life because of postoperative pancreatic dysfunction (such as digestive and absorption disorders) and fatty liver as a result of combined resection of the duodenum, gallbladder, and bile duct. The present study investigated the usefulness of pancrelipase for the prevention of pancreatic dysfunction after PD. The data from 73 patients who underwent PD in a single institution were analyzed. Patients who underwent PD during 2007-2011 were administered the low-titer pancreatic enzyme preparations berizym The second period group had significantly higher serum albumin concentrations at 3 and 6 months postoperatively, serum total cholesterol concentrations at 1 month postoperatively, and Onodera's PNI values at 3 and 6 months postoperatively than the first period group. The CONUT index values at 6 months after PD were significantly lower in the second period group than in the first period group. Pancrelipase is useful in improving the nutrition status and preventing fatty liver after PD.
Identifiants
pubmed: 35111504
doi: 10.20407/fmj.2018-016
pmc: PMC8766243
doi:
Types de publication
Journal Article
Langues
eng
Pagination
63-66Déclaration de conflit d'intérêts
The authors declare no competing financial interests.
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