Personalized dosimetry for a deeper understanding of metastatic response to high activity

131I-mIBG high activity therapy Dosimetry dose-response correlation high risk neuroblastoma

Journal

Quantitative imaging in medicine and surgery
ISSN: 2223-4292
Titre abrégé: Quant Imaging Med Surg
Pays: China
ID NLM: 101577942

Informations de publication

Date de publication:
Feb 2022
Historique:
received: 21 05 2021
accepted: 06 09 2021
entrez: 3 2 2022
pubmed: 4 2 2022
medline: 4 2 2022
Statut: ppublish

Résumé

Dosimetry in molecular radiotherapy for personalized treatment is assuming a central role in clinical management of aggressive/relapsed tumors. Relapsed/refractory metastatic high-risk neuroblastoma (rrmHR-NBL) has a poor prognosis and high-activity Fourteen patients affected by rrmHR-NBL were treated with high-activity The cumulative Our experience demonstrated feasibility of high activity therapy of

Sections du résumé

BACKGROUND BACKGROUND
Dosimetry in molecular radiotherapy for personalized treatment is assuming a central role in clinical management of aggressive/relapsed tumors. Relapsed/refractory metastatic high-risk neuroblastoma (rrmHR-NBL) has a poor prognosis and high-activity
METHODS METHODS
Fourteen patients affected by rrmHR-NBL were treated with high-activity
RESULTS RESULTS
The cumulative
CONCLUSIONS CONCLUSIONS
Our experience demonstrated feasibility of high activity therapy of

Identifiants

pubmed: 35111625
doi: 10.21037/qims-21-548
pii: qims-12-02-1299
pmc: PMC8739146
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1299-1310

Informations de copyright

2022 Quantitative Imaging in Medicine and Surgery. All rights reserved.

Déclaration de conflit d'intérêts

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://dx.doi.org/10.21037/qims-21-548). The authors have no conflicts of interest to declare

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Auteurs

Bartolomeo Cassano (B)

Medical Physics Unit, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.

Milena Pizzoferro (M)

Nuclear Medicine Unit/Imaging Department, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.

Silvio Valeri (S)

Medical Physics Unit, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.

Claudia Polito (C)

Medical Physics Unit, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.

Salvatore Donatiello (S)

Medical Physics Unit, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.

Claudio Altini (C)

Nuclear Medicine Unit/Imaging Department, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.

Maria Felicia Villani (MF)

Nuclear Medicine Unit/Imaging Department, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.

Annalisa Serra (A)

Department of Pediatric Hematology and Oncology, IRCCS Ospedale Pediatrico Bambino Gesu, Rome, Italy.

Aurora Castellano (A)

Nuclear Medicine Unit/Imaging Department, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.
Department of Pediatric Hematology and Oncology, IRCCS Ospedale Pediatrico Bambino Gesu, Rome, Italy.

Maria Carmen Garganese (MC)

Nuclear Medicine Unit/Imaging Department, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.

Vittorio Cannatà (V)

Medical Physics Unit, IRCCS Bambino Gesù Children's Hospital, Rome, Italy.

Classifications MeSH