The yin and yang of intracellular delivery of amphipathic optical probes using
Journal
Chemical communications (Cambridge, England)
ISSN: 1364-548X
Titre abrégé: Chem Commun (Camb)
Pays: England
ID NLM: 9610838
Informations de publication
Date de publication:
24 Feb 2022
24 Feb 2022
Historique:
pubmed:
4
2
2022
medline:
3
3
2022
entrez:
3
2
2022
Statut:
epublish
Résumé
Monitoring and manipulation of ionized intracellular calcium concentrations within intact, living cells using optical probes with organic chromophores is a core method for cell physiology. Since all these probes have multiple negative charges, they must be smuggled through the plasma membrane in a transiently neutral form, with intracellular esterases used to deprotect the masked anions. Here we explore the ability of the synthetically easily accessible
Identifiants
pubmed: 35112125
doi: 10.1039/d1cc06792c
pmc: PMC9502023
mid: NIHMS1785312
doi:
Substances chimiques
Fluorescent Dyes
0
Esterases
EC 3.1.-
Calcium
SY7Q814VUP
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2826-2829Subventions
Organisme : NIGMS NIH HHS
ID : R01 GM053395
Pays : United States
Organisme : NINDS NIH HHS
ID : R35 NS111600
Pays : United States
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