Aquaporin-5 in breast cancer.

Aquaporin 5 / genetics Breast Neoplasms / pathology Cell Adhesion Female Humans Lymphatic Metastasis Water / metabolism
aquaporin-5 biomarker breast cancer carcinoma migration proliferation

Journal

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica
ISSN: 1600-0463
Titre abrégé: APMIS
Pays: Denmark
ID NLM: 8803400

Informations de publication

Date de publication:
May 2022
Historique:
received: 05 01 2022
accepted: 27 01 2022
pubmed: 4 2 2022
medline: 12 4 2022
entrez: 3 2 2022
Statut: ppublish

Résumé

The water channel aquaporin-5 (AQP5) is essential in transepithelial water transport in secretory glands. AQP5 is ectopically overexpressed in breast cancer, where expression is associated with lymph node metastasis and poor prognosis. Besides the role in water transport, AQP5 has been found to play a role in cancer metastasis, migration, and proliferation. AQP5 has also been shown to be involved in the dysregulation of epithelial cell-cell adhesion; frequently observed in cancers. Insight into the underlying molecular mechanisms of how AQP5 contributes to cancer development and progression is essential for potentially implementing AQP5 as a prognostic biomarker and to develop targeted intervention strategies for the treatment of breast cancer patients.

Identifiants

DOI: 10.1111/apm.13212 PMID: 35114014 PMC: PMC9314690
pubmed: 35114014
doi: 10.1111/apm.13212
pmc: PMC9314690
doi:

Substances chimiques

Aquaporin 5 0
Water 059QF0KO0R

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

253-260

Informations de copyright

© 2022 The Authors. APMIS published by John Wiley & Sons Ltd on behalf of Scandinavian Societies for Medical Microbiology and Pathology.

Références

Am J Respir Cell Mol Biol. 2000 Jan;22(1):34-44
pubmed: 10615063
PLoS One. 2010 Dec 03;5(12):e14226
pubmed: 21151978
J Rheumatol. 2005 Jun;32(6):1071-5
pubmed: 15940770
Anticancer Agents Med Chem. 2020;20(4):417-428
pubmed: 31830896
Am J Pathol. 2008 Aug;173(2):518-25
pubmed: 18583321
Acta Oncol. 2018 Jan;57(1):3-12
pubmed: 29205077
J Biol Chem. 2005 Apr 22;280(16):15493-6
pubmed: 15746100
EMBO J. 1994 Jul 1;13(13):2985-93
pubmed: 7518771
Ann Nutr Metab. 2017;70 Suppl 1:37-42
pubmed: 28614812
Biochimie. 2021 Sep;188:52-60
pubmed: 33894294
Lab Invest. 2001 Feb;81(2):143-8
pubmed: 11232635
Nature. 2020 Feb;578(7795):437-443
pubmed: 32025032
Diabetes. 2002 Oct;51(10):2915-21
pubmed: 12351427
Int J Mol Sci. 2017 Jan 29;18(2):
pubmed: 28146084
Med Oncol. 2012 Sep;29(3):1998-2004
pubmed: 22048942
Cell Tissue Res. 1999 Mar;295(3):513-21
pubmed: 10022971
Tumour Biol. 2013 Jun;34(3):1743-51
pubmed: 23436048
Onco Targets Ther. 2018 Jun 06;11:3359-3368
pubmed: 29922074
J Surg Oncol. 2017 Jun;115(8):980-996
pubmed: 28471475
Pflugers Arch. 2008 Jul;456(4):693-700
pubmed: 17968585
Oncol Lett. 2018 Aug;16(2):2661-2667
pubmed: 30013662
Biochem Biophys Res Commun. 2008 Mar 7;367(2):291-8
pubmed: 18155156
CA Cancer J Clin. 2021 May;71(3):209-249
pubmed: 33538338
Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):511-6
pubmed: 11773623
Acta Histochem Cytochem. 2009 Dec 29;42(6):159-69
pubmed: 20126569
Hum Reprod Update. 2006 Nov-Dec;12(6):785-95
pubmed: 16840793
Clin Chem. 2017 Feb;63(2):532-541
pubmed: 27940449
J Clin Invest. 2000 Jan;105(1):93-100
pubmed: 10619865
Arch Gynecol Obstet. 2012 Feb;285(2):459-67
pubmed: 21698451
APMIS. 2022 May;130(5):253-260
pubmed: 35114014
Ann Diagn Pathol. 2020 Apr;45:151481
pubmed: 32120324
PLoS One. 2008 May 14;3(5):e2162
pubmed: 18478076
J Ovarian Res. 2014 Aug 15;7:78
pubmed: 25298246
Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3621-6
pubmed: 17360692
J Biol Chem. 1995 Jan 27;270(4):1908-12
pubmed: 7530250
Ann Surg Oncol. 2014 Feb;21(2):375-83
pubmed: 24114055
Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):13870-5
pubmed: 25189770
Histopathology. 2016 Jan;68(1):57-69
pubmed: 26768029
FASEB J. 2020 Feb;34(2):3379-3398
pubmed: 31922312
Breast Cancer Res Treat. 2010 Feb;120(1):67-76
pubmed: 19306058
Am J Physiol Cell Physiol. 2021 Mar 1;320(3):C282-C292
pubmed: 33175575
Cancers (Basel). 2021 Jul 22;13(15):
pubmed: 34359596
Nat Med. 2000 Feb;6(2):159-63
pubmed: 10655103
Lancet. 2001 Jun 23;357(9273):2054-5
pubmed: 11441861
APMIS. 2021 Dec;129(12):700-705
pubmed: 34582595
FASEB J. 2019 Jun;33(6):6980-6994
pubmed: 30840830
APMIS. 2022 Jan;130(1):3-10
pubmed: 34758159
PLoS One. 2011;6(12):e28492
pubmed: 22145049
Tumour Biol. 2014 Jul;35(7):7035-45
pubmed: 24752576
J Pathol. 2010 Jun;221(2):210-20
pubmed: 20455256
J Physiol. 2002 Jun 1;541(Pt 2):561-8
pubmed: 12042359
J Biol Chem. 1999 Jul 16;274(29):20071-4
pubmed: 10400615
Mol Carcinog. 2017 Dec;56(12):2692-2705
pubmed: 28833571
Bioinformatics. 2014 Mar 15;30(6):884-6
pubmed: 24162465
Biochem Biophys Res Commun. 2017 Nov 25;493(3):1210-1216
pubmed: 28958942
Lancet. 2001 Dec 1;358(9296):1875-6
pubmed: 11741631
Int J Mol Sci. 2017 Oct 07;18(10):
pubmed: 28991174
Am J Physiol Cell Physiol. 2021 May 1;320(5):C771-C777
pubmed: 33625928
Cytotechnology. 2018 Apr;70(2):615-624
pubmed: 29455395
Int J Biochem Cell Biol. 2016 Oct;79:271-276
pubmed: 27609140
Lancet. 2001 Mar 3;357(9257):688-9
pubmed: 11247557
J Surg Oncol. 2012 Sep 1;106(3):267-72
pubmed: 22105864
Science. 1994 Apr 1;264(5155):92-5
pubmed: 8140421

Auteurs

Malte Bystrup (M)

Department of Clinical Medicine, Aarhus University, Aarhus N, Denmark.
Department of Molecular Biology and Genetics, Aarhus University, Aarhus C, Denmark.

Frédéric H Login (FH)

Department of Clinical Medicine, Aarhus University, Aarhus N, Denmark.

Sarannya Edamana (S)

Department of Clinical Medicine, Aarhus University, Aarhus N, Denmark.

Signe Borgquist (S)

Department of Clinical Medicine, Aarhus University, Aarhus N, Denmark.
Department of Oncology, Aarhus University Hospital, Aarhus N, Denmark.
Department of Oncology, Clinical Sciences, Lund University, Lund, Sweden.

Trine Tramm (T)

Department of Clinical Medicine, Aarhus University, Aarhus N, Denmark.
Department of Pathology, Aarhus University Hospital, Aarhus N, Denmark.

Tae-Hwan Kwon (TH)

Department of Biochemistry and Cell Biology, School of Medicine, Kyungpook National University, Taegu, Korea.

Lene N Nejsum (LN)

Department of Clinical Medicine, Aarhus University, Aarhus N, Denmark.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Canaux ioniques › Porines › Aquaporines › Aquaporine-5 › Aquaporin-5 in breast cancer.
questionsmedicales.fr › Maladies de la peau et du tissu conjonctif › Maladies de la peau › Maladies du sein › Tumeurs du sein › Aquaporin-5 in breast cancer.
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Adhérence cellulaire › Aquaporin-5 in breast cancer.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Aquaporin-5 in breast cancer.
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Processus néoplasiques › Métastase tumorale › Métastase lymphatique › Aquaporin-5 in breast cancer.
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Oxydes › Eau › Aquaporin-5 in breast cancer.