MPO-ANCA positive interstitial pneumonia: Current knowledge and future perspectives.


Journal

Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG
ISSN: 2532-179X
Titre abrégé: Sarcoidosis Vasc Diffuse Lung Dis
Pays: Italy
ID NLM: 9610928

Informations de publication

Date de publication:
2022
Historique:
received: 21 05 2021
accepted: 16 06 2021
entrez: 4 2 2022
pubmed: 5 2 2022
medline: 5 2 2022
Statut: ppublish

Résumé

Although interstitial pneumonia is an important respiratory manifestation in microscopic polyangiitis (MPA), no studies have examined the detailed pathogenesis of interstitial pneumonia during the clinical course of MPA. In addition, it is considered that MPA develops at a certain incidence rate from myeloperoxidase (MPO)- antineutrophil cytoplasmic antibody (ANCA) positive interstitial pneumonia. However, there is a lack of consensus among pulmonologist and rheumatologist regarding whether MPO-ANCA positive interstitial pneumonia, which does not accompany other organ damage related to ANCA-associated vasculitis (AAV) other than interstitial pneumonia, should be included in AAV. In this review article, the clinical questions regarding MPO-ANCA positive interstitial pneumonia have been set, and evidence to date and problems to be solved in future are outlined.

Identifiants

pubmed: 35115752
doi: 10.36141/svdld.v38i4.11808
pii: SVDLD-38-45
pmc: PMC8787377
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

e2021045

Informations de copyright

Copyright: © 2021 SARCOIDOSIS VASCULITIS AND DIFFUSE LUNG DISEASES.

Déclaration de conflit d'intérêts

Each author declares that he or she has no commercial associations (e.g. consultancies, stock ownership, equity interest, patent/licensing arrangement etc.) that might pose a conflict of interest in connection with the submitted article.

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Auteurs

Masashi Bando (M)

Division of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Tochigi, Japan.

Sakae Homma (S)

Department of Advanced and Integrated Interstitial Lung Diseases Research, School of Medicine, Toho University, Tokyo, Japan.

Masayoshi Harigai (M)

Division of Rheumatology, Department of Internal Medicine, Tokyo Women's Medical University School of Medicine, Tokyo, Japan.

Classifications MeSH