Controversies in Gestational Diabetes.

Gestational diabetes mellitus glyburide insulin metformin screening treatment

Journal

TouchREVIEWS in endocrinology
ISSN: 2752-5457
Titre abrégé: touchREV Endocrinol
Pays: England
ID NLM: 101779126

Informations de publication

Date de publication:
Nov 2021
Historique:
received: 01 09 2020
accepted: 23 02 2021
entrez: 4 2 2022
pubmed: 5 2 2022
medline: 5 2 2022
Statut: ppublish

Résumé

Gestational diabetes mellitus (GDM) complicates approximately 7% of pregnancies in the USA. Despite recognition of the benefits of diagnosing and treating GDM, there are several areas of controversy that remain unresolved. There is debate as to whether to screen for GDM with the one-step versus the two-step approach. While the former identifies more pregnancies with potential adverse outcomes, data are lacking as to whether treatment of these pregnancies will improve outcomes, while increasing costs by diagnosing more women. Though it is well established that the diagnosis of even mild GDM, and treatment with lifestyle recommendations and insulin, improves pregnancy outcomes, it is controversial as to which type and regimen of insulin is optimal, and whether oral agents can be used safely and effectively to control glucose levels. Finally, it is recommended that women with GDM get tested for type 2 diabetes within several months of delivery; however, many women do not undergo this testing and alternative approaches are needed. These controversies are discussed with data from both sides of the debate to enable clinicians to make patient-centered decisions until more definitive data are available.

Identifiants

pubmed: 35118455
doi: 10.17925/EE.2021.17.2.102
pmc: PMC8676105
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

102-107

Informations de copyright

© Touch Medical Media 2021.

Déclaration de conflit d'intérêts

Disclosures: Chloe A Zera and Ellen W Seely have no financial or non-financial relationships or activities to declare in relation to this article.

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Auteurs

Chloe A Zera (CA)

Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, Boston, MA, USA.
Harvard Medical School, Boston, MA, USA.

Ellen W Seely (EW)

Harvard Medical School, Boston, MA, USA.
Division of Endocrinology, Diabetes and Hypertension, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.

Classifications MeSH