Reconnection patterns after CLOSE-guided 50 W high-power-short-duration circumferential pulmonary vein isolation and substrate modification-PV reconnection might no longer be an issue.

CLOSE protocol ablation index high-power-short-duration pulmonary vein isolation pulmonary vein reconnection reablation

Journal

Journal of cardiovascular electrophysiology
ISSN: 1540-8167
Titre abrégé: J Cardiovasc Electrophysiol
Pays: United States
ID NLM: 9010756

Informations de publication

Date de publication:
06 2022
Historique:
revised: 18 01 2022
received: 01 01 2022
accepted: 02 02 2022
pubmed: 5 2 2022
medline: 10 6 2022
entrez: 4 2 2022
Statut: ppublish

Résumé

Ablation of atrial fibrillation (AF) with high-power-short-duration (HPSD) radiofrequency (RF) technology is emerging as a new standard of care in many electrophysiology laboratories. While procedural short-term efficacy and efficiency is very promising, little is known about mid- to long-term effects of HPSD ablation for pulmonary vein isolation (PVI) and left atrial substrate modification. In a single-center registry, 412 AF procedures were performed in 400 individual patients using a standardized CLOSE protocol-guided fixed 50 W HPSD ablation, aiming for an ablation index (AI) of 400 on the posterior and 550 on the anterior wall. Additional substrate-tailored lines were performed when required. After a mean clinical follow-up of 337 ± 134 days, 15 patients suffered from AF recurrence beyond the blinding period. Twelve gave consent to the indicated reablation. Here, 11 of 12 patients had chronic isolation of all four pulmonary veins (PV). In three of six patients, a reconnection of additional left atrial ablation lines was revealed. Ten out of 12 patients showed progressive fibrous atrial cardiomyopathy and required additional left atrial substrate modification or reisolation of left-atrial lines. During the follow-up no clinical case of atrioesophageal fistula was registered. No PV stenosis after initial HPSD PVI was documented. Patients requiring reablation of AF or other atrial tachycardia after a fixed 50 W HPSD circumferential PVI and substrate modification predominantly suffer from progressive fibrous atrial cardiomyopathy, while PV reconnection appears to be a rare cause of AF recurrence.

Identifiants

pubmed: 35118734
doi: 10.1111/jce.15396
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1136-1145

Informations de copyright

© 2022 The Authors. Journal of Cardiovascular Electrophysiology published by Wiley Periodicals LLC.

Références

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Auteurs

Alexander Francke (A)

Department of EP, Helios Klinikum Pirna, Pirna, Germany.

Frank Scharfe (F)

Department of EP, Helios Klinikum Pirna, Pirna, Germany.

Steffen Schoen (S)

Department of EP, Helios Klinikum Pirna, Pirna, Germany.

Carsten Wunderlich (C)

Department of EP, Helios Klinikum Pirna, Pirna, Germany.

Marian Christoph (M)

Department of EP, Klinikum Chemnitz, TU Dresden Campus Chemnitz-MEDiC, Chemnitz, Germany.

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