Activation of PKC results in improved contractile effects and Ca

Animals Isoproterenol / pharmacology Mice Muscle Contraction Myocytes, Cardiac / metabolism Phosphorylation Protein Phosphatase 2 / metabolism
Ca2+ signaling protein kinase C protein phosphatase 2A protein phosphorylation regulatory subunit B56α

Journal

American journal of physiology. Heart and circulatory physiology
ISSN: 1522-1539
Titre abrégé: Am J Physiol Heart Circ Physiol
Pays: United States
ID NLM: 100901228

Informations de publication

Date de publication:
01 03 2022
Historique:
pubmed: 5 2 2022
medline: 4 5 2022
entrez: 4 2 2022
Statut: ppublish

Résumé

Protein phosphatase 2A (PP2A) represents a heterotrimer that is responsible for the dephosphorylation of important regulatory myocardial proteins. This study was aimed to test whether the phosphorylation of PP2A-B56α at Ser

Identifiants

DOI: 10.1152/ajpheart.00539.2021 PMID: 35119335
pubmed: 35119335
doi: 10.1152/ajpheart.00539.2021
doi:

Substances chimiques

Protein Phosphatase 2 EC 3.1.3.16
Isoproterenol L628TT009W

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

H427-H441

Commentaires et corrections

Type : CommentIn

Auteurs

Florentina Pluteanu (F)

Department of Anatomy, Animal Physiology and Biophysics, University of Bucharest, Bucharest, Romania.

Peter Boknik (P)

Institute of Pharmacology and Toxicology, University of Münster, Münster, Germany.

Alexander Heinick (A)

Institute of Pharmacology and Toxicology, University of Münster, Münster, Germany.

Christiane König (C)

Institute of Pharmacology and Toxicology, University of Münster, Münster, Germany.

Frank U Müller (FU)

Institute of Pharmacology and Toxicology, University of Münster, Münster, Germany.

Adam Weidlich (A)

Institute of Pharmacology and Toxicology, University of Münster, Münster, Germany.

Uwe Kirchhefer (U)

Institute of Pharmacology and Toxicology, University of Münster, Münster, Germany.
ORCID: 0000-0002-2838-2579

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Classifications MeSH

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questionsmedicales.fr › Métabolisme › Phosphorylation › Activation of PKC results in improved...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Phosphoprotein Phosphatases › Protein Phosphatase 2 › Activation of PKC results in improved...