Contribution of magnetic particles in molecular diagnosis of human viruses.
Detection
Enrichment
Extraction
Magnetic nanoparticles
Viruses
Journal
Talanta
ISSN: 1873-3573
Titre abrégé: Talanta
Pays: Netherlands
ID NLM: 2984816R
Informations de publication
Date de publication:
01 May 2022
01 May 2022
Historique:
received:
16
12
2021
revised:
17
01
2022
accepted:
18
01
2022
pubmed:
6
2
2022
medline:
22
2
2022
entrez:
5
2
2022
Statut:
ppublish
Résumé
Viral diseases are the primary source of death, making a worldwide influence on healthcare, social, and economic development. Thus, diagnosis is the vital approach to the main aim of virus control and elimination. On the other hand, the prompt advancement of nanotechnology in the field of medicine possesses the probability of being beneficial to diagnose infections normally in labs as well as specifically. Nanoparticles are efficiently in use to make novel strategies because of permitting analysis at cellular in addition to the molecular scale. Henceforth, they assist towards pronounced progress concerning molecular analysis at the nanoscale. In recent times, magnetic nanoparticles conjugated through covalent bonds to bioanalytes for instance peptides, antibodies, nucleic acids, plus proteins are established like nanoprobes aimed at molecular recognition. These modified magnetic nanoparticles could offer a simple fast approach for extraction, purification, enrichment/concentration, besides viruses' recognition precisely also specifically. In consideration of the above, herein insight and outlook into the limitations of conventional methods and numerous roles played by magnetic nanoparticles to extract, purify, concentrate, and additionally in developing a diagnostic regime for viral outbreaks to combat viruses especially the ongoing novel coronavirus (COVID-19).
Identifiants
pubmed: 35121538
pii: S0039-9140(22)00039-X
doi: 10.1016/j.talanta.2022.123243
pmc: PMC8779935
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
123243Informations de copyright
Copyright © 2022. Published by Elsevier B.V.
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