Assessment and Management of Immune Thrombocytopenia (ITP) in the Emergency Department: Current Perspectives.
ITP
diagnosis
symptoms
treatment
Journal
Open access emergency medicine : OAEM
ISSN: 1179-1500
Titre abrégé: Open Access Emerg Med
Pays: New Zealand
ID NLM: 101570796
Informations de publication
Date de publication:
2022
2022
Historique:
received:
09
11
2021
accepted:
20
01
2022
entrez:
7
2
2022
pubmed:
8
2
2022
medline:
8
2
2022
Statut:
epublish
Résumé
Immune thrombocytopenia (ITP) is characterized by a platelet count less than 100 × 10^9/L without anemia or leukopenia. Patients with ITP may be asymptomatic, or they may have mild bleeding like petechiae, purpura, or epistaxis. In rare cases, they may present to the emergency department (ED) with life-threatening bleeding as a result of their thrombocytopenia. The emergency physician should thus be prepared to diagnose ITP and treat the bleeding that can result from it. The diagnosis of ITP requires excluding secondary causes of thrombocytopenia, and in the ED, the bare minimum workup for ITP includes a complete blood count and a peripheral blood smear. The peripheral blood smear should show a small number of large platelets with normal morphology, and there should not be an increased number of schistocytes. Many patients with ITP require no emergent treatment. However, if a patient with suspected ITP presents to the ED with critical hemorrhage, the emergency physician should initiate treatment with a platelet transfusion, corticosteroids, and intravenous immune globulin (IVIG) as soon as possible. For less severe bleeding, platelet transfusions are not recommended, and the treatment consists of corticosteroids by themselves or in conjunction with IVIG.
Identifiants
pubmed: 35125895
doi: 10.2147/OAEM.S331675
pii: 331675
pmc: PMC8809484
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
25-34Informations de copyright
© 2022 Zitek et al.
Déclaration de conflit d'intérêts
The authors report no conflicts of interest in this work.
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