The impact of COVID-19 vaccine on sperm quality.
COVID-19
sperm count
sperm quality vaccine
Journal
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
ISSN: 1879-3479
Titre abrégé: Int J Gynaecol Obstet
Pays: United States
ID NLM: 0210174
Informations de publication
Date de publication:
Jul 2022
Jul 2022
Historique:
received:
25
10
2021
accepted:
02
02
2022
pubmed:
8
2
2022
medline:
18
6
2022
entrez:
7
2
2022
Statut:
ppublish
Résumé
To examine the effect of the BNT162b, mRNA, SARS-CoV-2 virus vaccine on sperm quality. This was a prospective cohort study conducted on sperm donors at the sperm bank of a tertiary, university affiliated medical center. All sperm donors donated sperm repeatedly and the average sperm parameters of all available samples were compared before and after receiving the SARS-CoV-2 vaccine. Each donor served as his own control. For all participants, at-least one sperm sample was received 72 days after completing the second vaccine. Main outcome measures included total sperm count, total motile count and percent of motile sperm. A total of 898 sperm samples from 33 sperm donors that were vaccinated with the Pfizer BNT162b, mRNA, SARS-CoV-2 virus vaccine were analyzed, 425 samples were received before the vaccine, while 473 samples were received after vaccination. Total sperm count and total motile count increased after the second vaccine compared to samples before vaccination. Percent of motile sperm did not change after vaccine. The Pfizer BNT162b, SARS-CoV-2 vaccine has no deleterious effect on sperm quality. Patients and physicians should be counseled accordingly.
Identifiants
pubmed: 35128663
doi: 10.1002/ijgo.14135
pmc: PMC9087610
doi:
Substances chimiques
COVID-19 Vaccines
0
RNA, Messenger
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
116-120Informations de copyright
© 2022 International Federation of Gynecology and Obstetrics.
Références
Psychol Med. 2020 Dec 11;:1-15
pubmed: 33305716
Vaccine. 2020 Sep 29;38(42):6500-6507
pubmed: 32863069
Hum Reprod Update. 2010 May-Jun;16(3):231-45
pubmed: 19934213
Vaccine. 2021 Jan 15;39(3):473-479
pubmed: 33358265
Pers Individ Dif. 2021 Jan 1;168:110289
pubmed: 32834288
Nature. 2020 Oct;586(7830):589-593
pubmed: 32785213
Int J Gynaecol Obstet. 2022 Jul;158(1):116-120
pubmed: 35128663
JAMA Netw Open. 2020 Oct 1;3(10):e2025594
pubmed: 33079199
EClinicalMedicine. 2020 Nov;28:100604
pubmed: 33134901
Nature. 2020 Dec;588(7838):377-378
pubmed: 33311629
N Engl J Med. 2020 Dec 31;383(27):2603-2615
pubmed: 33301246
Front Physiol. 2020 Nov 17;11:574761
pubmed: 33312128
Fertil Steril. 1988 Jan;49(1):112-7
pubmed: 3335257
EClinicalMedicine. 2020 Sep;26:100495
pubmed: 32838242