Multisystemic inflammatory syndrome related to COVID-19, with latent tuberculosis in bone marrow, and satisfactory response to tocilizumab, in a 7-year-old boy.
Journal
Reumatismo
ISSN: 0048-7449
Titre abrégé: Reumatismo
Pays: Italy
ID NLM: 0401302
Informations de publication
Date de publication:
07 Feb 2022
07 Feb 2022
Historique:
received:
15
08
2021
accepted:
11
11
2021
entrez:
8
2
2022
pubmed:
9
2
2022
medline:
10
2
2022
Statut:
epublish
Résumé
Paediatric inflammatory multisystem syndrome temporally associated with COVID-19 (PIMS-TS) or multisystem inflammatory syndrome in children (MIS-C) is a new acute-onset systemic inflammatory disease, which mainly affects children. Latent tuberculosis infection (LTBI) is characterized by the presence of immune sensitization to Mycobacterium tuberculosis (MTB) in the absence of any clinical or radiological evidence of active disease. We present a child with MIS-C related to COVID-19, with latent TB in the bone marrow, and satisfactory response to tocilizumab. It is important to pay attention in the investigation of TB cases in countries with a high prevalence of tuberculosis, especially when opting for immunusuppression.
Identifiants
pubmed: 35130686
doi: 10.4081/reumatismo.2021.1448
doi:
Substances chimiques
Antibodies, Monoclonal, Humanized
0
tocilizumab
I031V2H011
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM