Erythroblastic synartesis associated with lymphoproliferative disorder: There can be more than meets the eye.
Dyserythropoietic anemia
Lymphoproliferative diseases
Monoclonal gammopathy
Reticulocytopenia
Synartesis
Journal
Clinical immunology (Orlando, Fla.)
ISSN: 1521-7035
Titre abrégé: Clin Immunol
Pays: United States
ID NLM: 100883537
Informations de publication
Date de publication:
03 2022
03 2022
Historique:
received:
06
09
2021
accepted:
01
02
2022
pubmed:
9
2
2022
medline:
7
5
2022
entrez:
8
2
2022
Statut:
ppublish
Résumé
Erythroblastic synartesis is a rare cause of acquired dyserythropoiesis. Only 9 cases have been previously reported. We hereby report 3 cases of patients diagnosed with erythroblastic synartesis associated with monoclonal immunoglobulin and an overt malignant lymphoid disorder. A different B-cell clone may produce the monoclonal immunoglobulin, forming a biclonal disorder. In light of these data and literature review, treatment targeting the paraprotein seems to be efficient to control synartesis and correct anemia. In the case of monoclonal gammapathy associated with chronic lymphocytic leukemia, therapeutics should be adapted to control both chronic lymphocytic leukemia and monitored monoclonal immunoglobulin titer.
Identifiants
pubmed: 35134549
pii: S1521-6616(22)00031-6
doi: 10.1016/j.clim.2022.108951
pii:
doi:
Substances chimiques
Antibodies, Monoclonal
0
Types de publication
Case Reports
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
108951Informations de copyright
Copyright © 2022 Elsevier Inc. All rights reserved.