Childhood Maltreatment, Educational Attainment, and IQ: Findings From a Multicentric Case-control Study of First-episode Psychosis (EU-GEI).
IQ
childhood abuse
childhood neglect
psychosis
schizophrenia
Journal
Schizophrenia bulletin
ISSN: 1745-1701
Titre abrégé: Schizophr Bull
Pays: United States
ID NLM: 0236760
Informations de publication
Date de publication:
07 05 2022
07 05 2022
Historique:
pubmed:
10
2
2022
medline:
11
5
2022
entrez:
9
2
2022
Statut:
ppublish
Résumé
Evidence suggests that childhood maltreatment (ie, childhood abuse and childhood neglect) affects educational attainment and cognition. However, the association between childhood maltreatment and Intelligence Quotient (IQ) seems stronger among controls compared to people with psychosis. We hypothesised that: the association between childhood maltreatment and poor cognition would be stronger among community controls than among people with first-episode of psychosis (FEP); compared to abuse, neglect would show stronger associations with educational attainment and cognition; the association between childhood maltreatment and IQ would be partially accounted for by other risk factors; and the association between childhood maltreatment, educational attainment, and IQ would be stronger among patients with affective psychoses compared to those with nonaffective psychoses. 829 patients with FEP and 1283 community controls from 16 EU-GEI sites were assessed for child maltreatment, education attainment, and IQ. In both the FEP and control group, childhood maltreatment was associated with lower educational attainment. The association between childhood maltreatment and lower IQ was robust to adjustment for confounders only among controls. Whereas childhood neglect was consistently associated with lower attainment and IQ in both groups, childhood abuse was associated with IQ only in controls. Among both patients with affective and nonaffective psychoses, negative associations between childhood maltreatment and educational attainment were observed, but the crude association with IQ was only evident in affective psychoses. Our findings underscore the role of childhood maltreatment in shaping academic outcomes and cognition of people with FEP as well as controls.
Sections du résumé
BACKGROUND AND HYPOTHESIS
Evidence suggests that childhood maltreatment (ie, childhood abuse and childhood neglect) affects educational attainment and cognition. However, the association between childhood maltreatment and Intelligence Quotient (IQ) seems stronger among controls compared to people with psychosis. We hypothesised that: the association between childhood maltreatment and poor cognition would be stronger among community controls than among people with first-episode of psychosis (FEP); compared to abuse, neglect would show stronger associations with educational attainment and cognition; the association between childhood maltreatment and IQ would be partially accounted for by other risk factors; and the association between childhood maltreatment, educational attainment, and IQ would be stronger among patients with affective psychoses compared to those with nonaffective psychoses.
STUDY DESIGN
829 patients with FEP and 1283 community controls from 16 EU-GEI sites were assessed for child maltreatment, education attainment, and IQ.
STUDY RESULTS
In both the FEP and control group, childhood maltreatment was associated with lower educational attainment. The association between childhood maltreatment and lower IQ was robust to adjustment for confounders only among controls. Whereas childhood neglect was consistently associated with lower attainment and IQ in both groups, childhood abuse was associated with IQ only in controls. Among both patients with affective and nonaffective psychoses, negative associations between childhood maltreatment and educational attainment were observed, but the crude association with IQ was only evident in affective psychoses.
CONCLUSIONS
Our findings underscore the role of childhood maltreatment in shaping academic outcomes and cognition of people with FEP as well as controls.
Identifiants
pubmed: 35137235
pii: 6524686
doi: 10.1093/schbul/sbac004
pmc: PMC9077421
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
575-589Subventions
Organisme : Department of Health
Pays : United Kingdom
Investigateurs
Silvia Amoretti
(S)
Álvaro Andreu-Bernabeu
(Á)
Grégoire Baudin
(G)
Stephanie Beards
(S)
Chiara Bonetto
(C)
Elena Bonora
(E)
Bibiana Cabrera
(B)
Angel Carracedo
(A)
Thomas Charpeaud
(T)
Javier Costas
(J)
Doriana Cristofalo
(D)
Pedro Cuadrado
(P)
Manuel Durán-Cutilla
(M)
Aziz Ferchiou
(A)
David Fraguas
(D)
Nathalie Franke
(N)
Flora Frijda
(F)
Cloe Llorente
(C)
Paz Garcia-Portilla
(P)
Javier González Peñas
(J)
Kathryn Hubbard
(K)
Stéphane Jamain
(S)
Estela Jiménez-López
(E)
Marion Leboyer
(M)
Gonzalo López Montoya
(G)
Esther Lorente-Rovira
(E)
Covadonga M Díaz-Caneja
(C)
Camila Marcelino Loureiro
(C)
Mario Matteis
(M)
Elles Messchaart
(E)
Ma Dolores Moltó
(MD)
Gisela Mezquida
(G)
Carmen Moreno
(C)
Roberto Muratori
(R)
Nacher Juan
(N)
Mara Parellada
(M)
Baptiste Pignon
(B)
Marta Rapado-Castro
(M)
Mirella Ruggeri
(M)
Jean-Romain Richard
(JR)
José Juan Rodríguez Solano
(JJ)
Pilar A Sáiz
(PA)
Teresa Sánchez-Gutierrez
(T)
Emilio Sánchez
(E)
Franck Schürhoff
(F)
Marco Seri
(M)
Rosana Shuhama
(R)
Simona A Stilo
(SA)
Fabian Termorshuizen
(F)
Anne-Marie Tronche
(AM)
Daniella van Dam
(D)
Elsje van der Ven
(E)
Informations de copyright
© The Author(s) 2022. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For permissions, please email: journals.permissions@oup.com.
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