Systems on Top of Nasal Cannula Improve Oxygen Delivery in Patients with COVID-19: a Randomized Controlled Trial.
coronavirus disease 2019
double-trunk mask
hypoxemia
oxygen therapy
surgical mask
Journal
Journal of general internal medicine
ISSN: 1525-1497
Titre abrégé: J Gen Intern Med
Pays: United States
ID NLM: 8605834
Informations de publication
Date de publication:
04 2022
04 2022
Historique:
received:
19
11
2021
accepted:
14
01
2022
pubmed:
10
2
2022
medline:
5
4
2022
entrez:
9
2
2022
Statut:
ppublish
Résumé
Treating hypoxemia while meeting the soaring demands of oxygen can be a challenge during the COVID-19 pandemic. To determine the efficacy of the surgical facemask and the double-trunk mask on top of the low-flow oxygen nasal cannula on arterial partial pressure of oxygen (PaO Randomized controlled trial. Hospitalized adults with COVID-19 and hypoxemia treated with the low-flow nasal cannula were enrolled between November 13, 2020, and March 05, 2021. Patients were randomized in a 1:1:1 ratio to receive either the nasal cannula alone (control) or the nasal cannula covered by the surgical facemask or the double-trunk mask. Arterial blood gases were collected at baseline and 30 min after the use of each system. The oxygen output was adapted afterwards to retrieve the baseline pulse oxygen saturation. The final oxygen output value was recorded after another 30-min period. The primary outcome was the absolute change in PaO Arterial blood samples were successfully collected in 24/27 (8 per group) randomized patients. Compared to the nasal cannula alone, PaO The addition of the surgical facemask or the double-trunk mask above the nasal cannula improves arterial oxygenation and reduces oxygen consumption.
Sections du résumé
BACKGROUND
Treating hypoxemia while meeting the soaring demands of oxygen can be a challenge during the COVID-19 pandemic.
OBJECTIVE
To determine the efficacy of the surgical facemask and the double-trunk mask on top of the low-flow oxygen nasal cannula on arterial partial pressure of oxygen (PaO
DESIGN
Randomized controlled trial.
PARTICIPANTS
Hospitalized adults with COVID-19 and hypoxemia treated with the low-flow nasal cannula were enrolled between November 13, 2020, and March 05, 2021.
INTERVENTIONS
Patients were randomized in a 1:1:1 ratio to receive either the nasal cannula alone (control) or the nasal cannula covered by the surgical facemask or the double-trunk mask. Arterial blood gases were collected at baseline and 30 min after the use of each system. The oxygen output was adapted afterwards to retrieve the baseline pulse oxygen saturation. The final oxygen output value was recorded after another 30-min period.
MAIN MEASURES
The primary outcome was the absolute change in PaO
KEY RESULTS
Arterial blood samples were successfully collected in 24/27 (8 per group) randomized patients. Compared to the nasal cannula alone, PaO
CONCLUSIONS
The addition of the surgical facemask or the double-trunk mask above the nasal cannula improves arterial oxygenation and reduces oxygen consumption.
Identifiants
pubmed: 35137298
doi: 10.1007/s11606-022-07419-2
pii: 10.1007/s11606-022-07419-2
pmc: PMC8971207
doi:
Substances chimiques
Oxygen
S88TT14065
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Pagination
1226-1232Commentaires et corrections
Type : CommentIn
Informations de copyright
© 2022. The Author(s) under exclusive licence to Society of General Internal Medicine.
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