Ocular anterior segment and corneal parameters evaluation in celiac disease.
Adolescent
Adult
Aged
Anterior Chamber
Anterior Eye Segment
/ diagnostic imaging
Astigmatism
Case-Control Studies
Celiac Disease
/ complications
Cornea
/ diagnostic imaging
Corneal Topography
Diagnostic Techniques, Ophthalmological
Female
Humans
Male
Middle Aged
Pupil
Tomography
Visual Acuity
Young Adult
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
09 02 2022
09 02 2022
Historique:
received:
02
09
2021
accepted:
21
01
2022
entrez:
10
2
2022
pubmed:
11
2
2022
medline:
5
3
2022
Statut:
epublish
Résumé
This observational case-control study evaluated the anterior ocular segment parameters of patients with celiac disease with a Scheimpflug imaging system and compared them with those of a healthy controls group, highlighting potential differences related to the underlying pathogenetic mechanisms of the disease. Seventy celiac patients and 70 healthy subjects were assessed with a comprehensive ophthalmological evaluation, including clinical history, Snellen best-corrected visual acuity, axial length (AL) measurements with IOLMaster, and anterior segment tomographic evaluation with Pentacam HR. The measurements of all keratometry values, astigmatism, steep axis, anterior and posterior Q value (asphericity), pupil diameter, pupil center, corneal apex, the thinnest point, corneal volume, anterior chamber depth from the epithelium, anterior chamber depth from endothelium, anterior chamber volume, and iridocorneal angle were also appraised. The two study groups were comparable and similar for gender, age, and AL, with no statistically significant differences regarding all analyzed tomographic parameters. Thus, ocular anterior segment parameters of celiac patients are not significantly different from those of healthy subjects, suggesting no underlying pathogenetic implications of celiac disease affecting the assessed structures. Nevertheless, a routine ophthalmological examination for all celiac patients should be recommended throughout their lifetimes due to the potential ocular manifestations of the disease.
Identifiants
pubmed: 35140276
doi: 10.1038/s41598-022-06058-1
pii: 10.1038/s41598-022-06058-1
pmc: PMC8828852
doi:
Types de publication
Journal Article
Observational Study
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2203Informations de copyright
© 2022. The Author(s).
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