Local Electrical Impedance Mapping of the Atria: Conclusions on Substrate Properties and Confounding Factors.

The treatment of atrial fibrillation and other cardiac arrhythmias as a major cause of cardiovascular hospitalization has remained a challenge predominantly for patients with severely remodeled substrate. Individualized ablation strategies are extremely important both for pulmonary vein isolation and subsequent ablations. Current approaches to identifying arrhythmogenic regions rely on electrogram-based features such as activation time and voltage. Novel technologies now enable clinical assessment of the local impedance as tissue property. Previous studies demonstrated its use for ablation monitoring and indicated its potential to differentiate healthy substrate, scar, and pathological tissue. This study investigates the potential of local electrical impedance-based substrate mapping of the atria for human

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Copyright © 2022 Unger, Schicketanz, Oesterlein, Stritt, Haas, Martínez Antón, Schmidt, Doessel and Luik.

Déclaration de conflit d'intérêts

TO is employed by Boston Scientific, Ratingen, Germany. AL is a consultant for Boston Scientific and has received speakers-fees from Boston Scientific, Biosense Webster and Bristol-Myers Squibb. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.