Low Back Pain With Persistent Radiculopathy; the Clinical Role of Genetic Variants in the Genes SOX5, CCDC26/GSDMC and DCC.

biomarkers candidate gene study (CGS) genetic susceptibility low back pain lumbar radiculopathy

Journal

Frontiers in genetics
ISSN: 1664-8021
Titre abrégé: Front Genet
Pays: Switzerland
ID NLM: 101560621

Informations de publication

Date de publication:
2021
Historique:
received: 06 09 2021
accepted: 29 12 2021
entrez: 10 2 2022
pubmed: 11 2 2022
medline: 11 2 2022
Statut: epublish

Résumé

In a recently published genome-wide association study (GWAS) chronic back pain was associated with three loci;

Identifiants

pubmed: 35140737
doi: 10.3389/fgene.2021.757632
pii: 757632
pmc: PMC8819060
doi:

Types de publication

Journal Article

Langues

eng

Pagination

757632

Informations de copyright

Copyright © 2022 Lie, Pedersen, Heuch, Winsvold, Gjerstad, Hasvik, Nygaard, Grotle, Matre, Zwart and Nilsen.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Références

Mol Neurobiol. 2016 Oct;53(8):5640-51
pubmed: 26482371
Am J Epidemiol. 2006 Oct 1;164(7):609-14
pubmed: 16893921
PLoS One. 2012;7(3):e31861
pubmed: 22396742
Development. 2003 Mar;130(6):1135-48
pubmed: 12571105
PLoS Genet. 2018 Sep 27;14(9):e1007601
pubmed: 30261039
Pain. 2000 Jan;84(1):95-103
pubmed: 10601677
Int J Immunogenet. 2020 Dec;47(6):546-553
pubmed: 32333499
Dev Cell. 2001 Aug;1(2):277-90
pubmed: 11702786
Int J Gen Med. 2010 Jul 21;3:209-14
pubmed: 20689695
Semin Cell Dev Biol. 2017 Feb;62:34-49
pubmed: 27771362
Biochim Biophys Acta Mol Cell Res. 2021 Mar;1868(3):118931
pubmed: 33340546
Spine (Phila Pa 1976). 2012 Dec 1;37(25):2074-81
pubmed: 22588384
Spine (Phila Pa 1976). 2008 Oct 15;33(22):2464-72
pubmed: 18923325
Br J Anaesth. 2007 Oct;99(4):461-73
pubmed: 17704089
Ann Rheum Dis. 2013 Jul;72(7):1141-8
pubmed: 22993228
Genet Med. 2019 Aug;21(8):1705-1707
pubmed: 30635622
Best Pract Res Clin Rheumatol. 2010 Apr;24(2):167-79
pubmed: 20227639
BMC Public Health. 2013 Dec 24;13:1229
pubmed: 24365383
Eur Spine J. 2018 Nov;27(11):2875-2881
pubmed: 30155730
Nucleic Acids Res. 2015 Sep 30;43(17):8183-203
pubmed: 26150426
Sci Rep. 2016 Sep 30;6:34460
pubmed: 27686527
Genome Med. 2021 Jan 28;13(1):14
pubmed: 33509269
Spine (Phila Pa 1976). 2017 Mar;42(5):E272-E279
pubmed: 28244968
Acta Biochim Biophys Sin (Shanghai). 2020 May 26;52(5):467-474
pubmed: 32294153
Nat Commun. 2017 Feb 22;8:14265
pubmed: 28223688
BMC Musculoskelet Disord. 2016 Dec 13;17(1):500
pubmed: 27964712
Pathobiology. 2008;75(3):195-9
pubmed: 18550917
Osteoarthritis Cartilage. 2016 May;24(5):835-43
pubmed: 26746145
Sci Rep. 2017 Apr 24;7:46704
pubmed: 28436462
Nat Rev Genet. 2019 Aug;20(8):467-484
pubmed: 31068683
Lancet. 2020 Oct 17;396(10258):1204-1222
pubmed: 33069326
PLoS One. 2016 Oct 20;11(10):e0163877
pubmed: 27764105
Sci Rep. 2020 Dec 3;10(1):21069
pubmed: 33273635

Auteurs

Marie Udnesseter Lie (MU)

Research and Communication Unit for Musculoskeletal Health (FORMI), Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway.
Faculty of Medicine, University of Oslo, Oslo, Norway.

Linda Margareth Pedersen (LM)

Department of Research, Innovation and Education, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway.
Department of Physiotherapy, Oslo Metropolitan University, Oslo, Norway.

Ingrid Heuch (I)

Department of Research, Innovation and Education, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway.

Bendik Winsvold (B)

Department of Research, Innovation and Education, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway.
Department of Neurology, Oslo University Hospital, Oslo, Norway.

Johannes Gjerstad (J)

Department of Work Psychology and Physiology, National Institute of Occupational Health, Oslo, Norway.
Department of Bioscience, University of Oslo, Oslo, Norway.

Eivind Hasvik (E)

Department of Physical Medicine and Rehabilitation, Østfold Hospital Trust, Grålum, Norway.

Øystein Petter Nygaard (ØP)

Department of Neurosurgery, St Olavs University Hospital, Trondheim, Norway.
Department of Neuroscience, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.
National Advisory Unit on Spinal Surgery, St Olavs Hospital, Trondheim, Norway.

Margreth Grotle (M)

Research and Communication Unit for Musculoskeletal Health (FORMI), Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway.
Department of Physiotherapy, Oslo Metropolitan University, Oslo, Norway.

Dagfinn Matre (D)

Department of Work Psychology and Physiology, National Institute of Occupational Health, Oslo, Norway.

John-Anker Zwart (JA)

Faculty of Medicine, University of Oslo, Oslo, Norway.
Department of Research, Innovation and Education, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway.

Kristian Bernhard Nilsen (KB)

Department of Neurology, Oslo University Hospital, Oslo, Norway.

Classifications MeSH