Successful treatment of refractory hypertension with bilateral nephrectomy in a patient with chronic kidney disease stage 3.
nephrectomy
refractory hypertension
renal denervation
sympathetic nervous system
Journal
Clinical kidney journal
ISSN: 2048-8505
Titre abrégé: Clin Kidney J
Pays: England
ID NLM: 101579321
Informations de publication
Date de publication:
Feb 2022
Feb 2022
Historique:
received:
22
06
2021
entrez:
11
2
2022
pubmed:
12
2
2022
medline:
12
2
2022
Statut:
epublish
Résumé
We present a case of life-threatening refractory hypertension (rHTN) in a patient with stage 3b chronic kidney disease that was unresponsive to open surgical renal denervation (RDN) but responded to bilateral nephrectomy (BLN). Both RDN and BLN reduce the increased sympathetic activation in rHTN. However, RDN has yet to show reductions in blood pressure adequate for the average patient with rHTN, and BLN has thus far been reserved for patients with preexisting end-stage kidney disease (ESKD). Our case suggests that there are patients with rHTN that warrant consideration of BLN prior to developing ESKD.
Identifiants
pubmed: 35145649
doi: 10.1093/ckj/sfab179
pii: sfab179
pmc: PMC8824767
doi:
Types de publication
Journal Article
Langues
eng
Pagination
347-350Informations de copyright
© The Author(s) 2021. Published by Oxford University Press on behalf of the ERA.
Références
Ann Intern Med. 1972 May;76(5):733-9
pubmed: 5063497
Cureus. 2020 Jul 6;12(7):e9031
pubmed: 32775110
J Clin Invest. 1935 Jul;14(4):443-58
pubmed: 16694318
N Engl J Med. 1970 Jul 30;283(5):222-4
pubmed: 4912789
Am J Physiol Regul Integr Comp Physiol. 2010 Feb;298(2):R245-53
pubmed: 19955493
J Am Soc Hypertens. 2014 Aug;8(8):593-8
pubmed: 25151320
J Clin Hypertens (Greenwich). 2020 Apr;22(4):572-584
pubmed: 32049436
Eur Heart J. 2015 Jan 21;36(4):199-202
pubmed: 25400163
Ann Surg. 1949 Jun;129(6):850-71
pubmed: 17859363
Hypertension. 2015 Feb;65(2):393-400
pubmed: 25403610
Am J Hypertens. 1998 Nov;11(11 Pt 1):1364-70
pubmed: 9832181
J Am Med Assoc. 1953 Aug 15;152(16):1501-4
pubmed: 13061307
Br Med J. 1959 Jan 17;1(5115):142-4
pubmed: 13618577
N Engl J Med. 1973 Jul 26;289(4):167-71
pubmed: 4268267
J Natl Med Assoc. 1980 May;72(5):453-7
pubmed: 6991710