The Gingiva of Horses With Pituitary Pars Intermedia Dysfunction: A Macroscopic Anatomical Evaluation.
PPID
dental examination
equine
gingival margin
periodontal disease
pituitary gland
Journal
Frontiers in veterinary science
ISSN: 2297-1769
Titre abrégé: Front Vet Sci
Pays: Switzerland
ID NLM: 101666658
Informations de publication
Date de publication:
2021
2021
Historique:
received:
30
09
2021
accepted:
10
12
2021
entrez:
11
2
2022
pubmed:
12
2
2022
medline:
12
2
2022
Statut:
epublish
Résumé
Pituitary pars intermedia dysfunction (PPID) is a common neurodegenerative disease mainly in horses older than 15 years. The domestic equine population is following the same demographic change as that seen in humans; it is aging and veterinarians are asked to attend to geriatric horses more frequently. Common problems seen regularly in older equines are dental disorders and especially periodontal disease. As a systemic and endocrine disease, associated with delayed wound healing and impaired immune function, PPID should be considered before major dental treatment in aged equines is started. Possible negative effects of PPID on epithelial tissues could also affect the periodontium. Therefore, the aim of the present study was to identify gross changes in the gingiva associated with PPID. Fourteen horses with clinical signs of PPID and adenoma in the pituitary pars intermedia and 13 controls showing neither clinical signs nor PPID-associated histological changes in the pituitary gland were included. PPID-affected horses (26.9 ± 0.73 years) were significantly older than controls (20.0 ± 1.24 years). In the PPID-affected group, significantly more often an irregular and bulky appearance of the gingival texture was observed, as well as an irregular shape of the gingival margin. Furthermore, the
Identifiants
pubmed: 35146012
doi: 10.3389/fvets.2021.786971
pmc: PMC8821874
doi:
Types de publication
Journal Article
Langues
eng
Pagination
786971Informations de copyright
Copyright © 2022 Nitzsche, Fey, Büttner, Gröf and Staszyk.
Déclaration de conflit d'intérêts
KF has a consultancy agreement with Boehringer Ingelheim Vetmedica. The remaining authors declare that this study was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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