Intravitreal anti-vascular endothelial growth factor injections to treat post-trabeculectomy Swan syndrome.

Anti-vascular endothelial growth factors Swan syndrome Trabeculectomy Wound neovascularization

Journal

American journal of ophthalmology case reports
ISSN: 2451-9936
Titre abrégé: Am J Ophthalmol Case Rep
Pays: United States
ID NLM: 101679941

Informations de publication

Date de publication:
Mar 2022
Historique:
received: 21 01 2021
revised: 10 03 2021
accepted: 20 01 2022
entrez: 11 2 2022
pubmed: 12 2 2022
medline: 12 2 2022
Statut: epublish

Résumé

To report a case of wound neovascularization (Swan syndrome) one year after trabeculectomy favorably treated with two intravitreal ranibizumab injections. A 79-year-old woman under coumadin treatment for atrial fibrillation experienced relapsing decreased vision in her left eye due to vitreous hemorrhage. She had had a past history of ocular hypertension corneal decompensation after phacoemulsification that required a Descemet Membrane Endothelial Keratoplasty and a subsequent trabeculectomy. After clearance of the hemorrhage, examination showed neovascularization not in the retina but surrounding the sclerostomy wound of the trabeculectomy, being diagnosed as a Swan syndrome. After two intravitreal injections of ranibizumab, gonioscopy showed complete resolution of the new vessels. No further recurrences have been reported and IOP has remained controlled without glaucomatous changes 7 months after the last injection. Clinical features and patient characteristics are described. Anti-vascular endothelial growth factor intravitreal injections may be a good and safe alternative to manage vitreous hemorrhage secondary to wound neovascularization of the trabeculectomy site.

Identifiants

pubmed: 35146202
doi: 10.1016/j.ajoc.2022.101332
pii: S2451-9936(22)00078-0
pmc: PMC8818482
doi:

Types de publication

Case Reports

Langues

eng

Pagination

101332

Informations de copyright

© 2022 Published by Elsevier Inc.

Déclaration de conflit d'intérêts

We wish to confirm that there are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome.

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Auteurs

Silvia Feu-Basilio (S)

Ophthalmology Institute, Hospital Clínic de Barcelona, Barcelona University (UB), Barcelona, Spain.

Barbara Romero-Nuñez (B)

Ophthalmology Institute, Hospital Clínic de Barcelona, Barcelona University (UB), Barcelona, Spain.

Néstor Ventura-Abreu (N)

Ophthalmology Institute, Hospital Clínic de Barcelona, Barcelona University (UB), Barcelona, Spain.
PhD Program, Instituto de Investigaciones Oftalmológicas Ramón Castroviejo, Department of Immunology, Ophthalmology and ORL, Faculty of Medicine, Complutense University of Madrid (UCM), Madrid, Spain.

Josep Torras-Sanvicens (J)

Ophthalmology Institute, Hospital Clínic de Barcelona, Barcelona University (UB), Barcelona, Spain.
Institut d'Investigacions Mèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

Marc Figueras-Roca (M)

Ophthalmology Institute, Hospital Clínic de Barcelona, Barcelona University (UB), Barcelona, Spain.
Institut d'Investigacions Mèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

Marta Pazos (M)

Ophthalmology Institute, Hospital Clínic de Barcelona, Barcelona University (UB), Barcelona, Spain.
Institut d'Investigacions Mèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

Classifications MeSH