Manganese(II) EOB-Pyclen Diacetate for Liver-Specific MRI.
MRI
contrast agent
liver specific
manganese
molecular imaging
Journal
ACS applied bio materials
ISSN: 2576-6422
Titre abrégé: ACS Appl Bio Mater
Pays: United States
ID NLM: 101729147
Informations de publication
Date de publication:
21 02 2022
21 02 2022
Historique:
pubmed:
12
2
2022
medline:
9
4
2022
entrez:
11
2
2022
Statut:
ppublish
Résumé
MRI is increasingly utilized for the diagnosis of liver disease and focal liver lesions. Although liver-targeted gadolinium-based contrast agents (GBCAs) have high efficacy, there continue to be safety concerns regarding release of toxic Gd(III) ions. Herein, Mn(EOB-PC2A) is synthesized as a nongadolinium alternative for liver-specific MRI. Mn(EOB-PC2A) has an
Identifiants
pubmed: 35148050
doi: 10.1021/acsabm.1c01259
doi:
Substances chimiques
Azabicyclo Compounds
0
Contrast Media
0
Ions
0
pyclen
0
Manganese
42Z2K6ZL8P
Gadolinium DTPA
K2I13DR72L
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
451-458Subventions
Organisme : NCI NIH HHS
ID : R01 CA211762
Pays : United States