Acute shear stress and vein graft disease.
Intimal hyperplasia
Shear stress
Vascular inflammation
Veins grafts
Journal
The international journal of biochemistry & cell biology
ISSN: 1878-5875
Titre abrégé: Int J Biochem Cell Biol
Pays: Netherlands
ID NLM: 9508482
Informations de publication
Date de publication:
03 2022
03 2022
Historique:
received:
19
08
2021
revised:
08
12
2021
accepted:
08
02
2022
pubmed:
14
2
2022
medline:
6
5
2022
entrez:
13
2
2022
Statut:
ppublish
Résumé
The long saphenous vein is commonly used in cardiac surgery to bypass occluded coronary arteries. Its use is complicated by late stenosis and occlusion due to the development of intimal hyperplasia. It is accepted that intimal hyperplasia is a multifactorial inflammatory process that starts immediately after surgery. The role of acute changes in haemodynamic conditions when the vein is implanted into arterial circulation, especially shear stress, is not fully appreciated. This review provides an overview of intimal hyperplasia and the effect of acute shear stress changes on the activation of pro-inflammatory mediators.
Identifiants
pubmed: 35151879
pii: S1357-2725(22)00018-8
doi: 10.1016/j.biocel.2022.106173
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
106173Informations de copyright
Copyright © 2022 Elsevier Ltd. All rights reserved.