Active Topological Glass Confined within a Spherical Cavity.
Journal
Macromolecules
ISSN: 0024-9297
Titre abrégé: Macromolecules
Pays: United States
ID NLM: 0365316
Informations de publication
Date de publication:
08 Feb 2022
08 Feb 2022
Historique:
received:
01
12
2021
revised:
13
01
2022
entrez:
14
2
2022
pubmed:
15
2
2022
medline:
15
2
2022
Statut:
ppublish
Résumé
We study active topological glass under spherical confinement, allowing us to exceed the chain lengths simulated previously and determine the critical exponents of the arrested conformations. We find a previously unresolved "tank-treading" dynamic mode of active segments along the ring contour. This mode can enhance active-passive phase separation in the state of active topological glass when both diffusional and conformational relaxation of the rings are significantly suppressed. Within the observational time, we see no systematic trends in the positioning of the separated active domains within the confining sphere. The arrested state exhibits coherent stochastic rotations. We discuss possible connections of the conformational and dynamic features of the system to chromosomes enclosed in the nucleus of a living cell.
Identifiants
pubmed: 35153336
doi: 10.1021/acs.macromol.1c02471
pmc: PMC8830202
doi:
Types de publication
Journal Article
Langues
eng
Pagination
956-964Subventions
Organisme : NIGMS NIH HHS
ID : R25 GM067110
Pays : United States
Informations de copyright
© 2022 The Authors. Published by American Chemical Society.
Déclaration de conflit d'intérêts
The authors declare no competing financial interest.
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