Comparison of enzyme-linked immunosorbent assay and Fassisi

antibody concentration calves colostrum passive transfer rapid method

Journal

Veterinary world
ISSN: 0972-8988
Titre abrégé: Vet World
Pays: India
ID NLM: 101504872

Informations de publication

Date de publication:
Dec 2021
Historique:
received: 03 06 2021
accepted: 08 11 2021
entrez: 14 2 2022
pubmed: 15 2 2022
medline: 15 2 2022
Statut: ppublish

Résumé

Rapid tests are routinely used to estimate serum immunoglobulin G (IgG) concentrations in diagnosing a failure of passive transfer (FPT) in calves. The study aimed to compare the Fassisi A total of 277 calves of 1-10 days of age were used in this study. Blood samples were obtained, and serum was extracted by centrifuging the samples at 2740× The mean ELISA-IgG serum concentration was 8.40 mg/mL (SD=7.02, range=0.10-47.50 mg/mL). FPT prevalence based on the ELISA measurements was 66.8%. The prevalence of partial and full FPT based on the FB-IgG was 54.5%. The ELISA-IgG and FB-IgG results were subjected to correlation and regression analysis. Overall sensitivity and specificity of the FB-IgG were 61.1% and 58.7%, respectively. A statistically significant dependence on age was identified in the results. Our findings suggest that the FB-IgG rapid method is less accurate and provides no other advantages over established methods.

Sections du résumé

BACKGROUND AND AIM OBJECTIVE
Rapid tests are routinely used to estimate serum immunoglobulin G (IgG) concentrations in diagnosing a failure of passive transfer (FPT) in calves. The study aimed to compare the Fassisi
MATERIALS AND METHODS METHODS
A total of 277 calves of 1-10 days of age were used in this study. Blood samples were obtained, and serum was extracted by centrifuging the samples at 2740×
RESULTS RESULTS
The mean ELISA-IgG serum concentration was 8.40 mg/mL (SD=7.02, range=0.10-47.50 mg/mL). FPT prevalence based on the ELISA measurements was 66.8%. The prevalence of partial and full FPT based on the FB-IgG was 54.5%. The ELISA-IgG and FB-IgG results were subjected to correlation and regression analysis. Overall sensitivity and specificity of the FB-IgG were 61.1% and 58.7%, respectively. A statistically significant dependence on age was identified in the results.
CONCLUSION CONCLUSIONS
Our findings suggest that the FB-IgG rapid method is less accurate and provides no other advantages over established methods.

Identifiants

pubmed: 35153414
doi: 10.14202/vetworld.2021.3211-3215
pii: Vetworld-14-3211
pmc: PMC8829403
doi:

Types de publication

Journal Article

Langues

eng

Pagination

3211-3215

Informations de copyright

Copyright: © Hampe, et al.

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Auteurs

Marian Hampe (M)

Clinic for Obstetrics, Gynecology, and Andrology of Large and Small Animals with Veterinary Ambulance, Justus-Liebig-University, D 35392 Giessen, Germany.

Stefanie Söllner-Donat (S)

Animal Health Service, Thuringian Animal Diseases Fund, Jena, Germany.

Klaus Failing (K)

Unit for Biomathematics and Data Processing, Justus-Liebig University, D 35392, Giessen, Germany.

Axel Wehrend (A)

Clinic for Obstetrics, Gynecology, and Andrology of Large and Small Animals with Veterinary Ambulance, Justus-Liebig-University, D 35392 Giessen, Germany.

Classifications MeSH