Sphingosine Kinase-1 Is Overexpressed and Correlates with Hypoxia in Osteosarcoma: Relationship with Clinicopathological Parameters.
FTY720
GLUT-1
HIF
S1P1
fingolimod
osteosarcoma
sphingosine kinase
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
19 Jan 2022
19 Jan 2022
Historique:
received:
08
12
2021
revised:
14
01
2022
accepted:
16
01
2022
entrez:
15
2
2022
pubmed:
16
2
2022
medline:
16
2
2022
Statut:
epublish
Résumé
The Sphingosine kinase-1/Sphingosine 1-Phosphate (SphK1/S1P) signaling pathway is overexpressed in various cancers, and is instrumental for the adaptation to hypoxia in a number of solid tumor models, but no data are available in osteosarcoma. Here we report that SphK1 and the S1P
Identifiants
pubmed: 35158767
pii: cancers14030499
doi: 10.3390/cancers14030499
pmc: PMC8833796
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Ligue Nationale contre le Cancer
ID : NA
Références
Crit Rev Oncol Hematol. 2020 Dec;156:103126
pubmed: 33113487
J Biol Chem. 2011 May 27;286(21):18633-40
pubmed: 21464128
Springerplus. 2016 Aug 19;5(1):1370
pubmed: 27606158
N Engl J Med. 2010 Feb 4;362(5):402-15
pubmed: 20089954
Vet Comp Oncol. 2008 Jun;6(2):133-40
pubmed: 19178673
Cancer Lett. 2015 Feb 1;357(1):254-264
pubmed: 25444927
PLoS One. 2019 Mar 7;14(3):e0213203
pubmed: 30845158
Clin Cancer Res. 2010 Dec 15;16(24):5928-35
pubmed: 20962028
J Clin Oncol. 2008 Feb 1;26(4):633-8
pubmed: 18235123
J Exp Clin Cancer Res. 2015 Feb 28;34:22
pubmed: 25884381
Cancer Metastasis Rev. 2007 Jun;26(2):225-39
pubmed: 17440684
Mol Cancer Ther. 2012 Sep;11(9):1841-51
pubmed: 22784711
Cancers (Basel). 2021 Jan 15;13(2):
pubmed: 33467731
J Cell Physiol. 2011 Jun;226(6):1425-32
pubmed: 21321933
Cancer Res. 2002 Mar 1;62(5):1410-9
pubmed: 11888913
Int J Biol Markers. 2016 Jul 30;31(3):e229-34
pubmed: 27312586
Pediatr Blood Cancer. 2013 Sep;60(9):1418-23
pubmed: 23704073
Cancer Res. 2003 Sep 15;63(18):5962-9
pubmed: 14522923
Lancet Oncol. 2016 Jul;17(7):896-906
pubmed: 27237614
Pathologe. 1983 May;4(3):135-41
pubmed: 6576329
FASEB J. 2004 Mar;18(3):551-3
pubmed: 14715694
J Clin Oncol. 2015 Jul 10;33(20):2279-87
pubmed: 26033801
Cell Rep. 2014 Apr 10;7(1):104-12
pubmed: 24703847
Eur J Cancer. 2010 Dec;46(18):3417-24
pubmed: 20970322
PLoS One. 2014 Mar 11;9(3):e90518
pubmed: 24618817
Nat Rev Drug Discov. 2013 Sep;12(9):688-702
pubmed: 23954895
Adv Cancer Res. 2013;117:117-41
pubmed: 23290779
PLoS One. 2013 Jun 13;8(6):e65304
pubmed: 23785417
Lancet Oncol. 2016 Aug;17(8):1070-1080
pubmed: 27324280
Cell Death Differ. 2001 Feb;8(2):162-71
pubmed: 11313718
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Aug;106(2):254-7
pubmed: 18554951
Jpn J Clin Oncol. 2007 Feb;37(2):127-34
pubmed: 17237146
EMBO J. 2003 Oct 15;22(20):5491-500
pubmed: 14532121
Int J Clin Oncol. 2015 Dec;20(6):1233-43
pubmed: 26077139
Nat Rev Cancer. 2002 Jan;2(1):38-47
pubmed: 11902584
Onco Targets Ther. 2021 Feb 11;14:995-1002
pubmed: 33603404
Cancer Res. 2009 May 1;69(9):3723-6
pubmed: 19383898
Nat Rev Cancer. 2014 Nov;14(11):722-35
pubmed: 25319867
BMC Cancer. 2010 Jul 16;10:372
pubmed: 20637078
Cancers (Basel). 2020 Dec 30;13(1):
pubmed: 33396725
Clin Orthop Relat Res. 2015 Jan;473(1):305-10
pubmed: 25193692
Oncogenesis. 2016 Mar 14;5:e209
pubmed: 26974204
PLoS One. 2014 Feb 27;9(2):e90362
pubmed: 24587339
Oncotarget. 2015 May 30;6(15):13803-21
pubmed: 25915662
Cell. 2012 Feb 3;148(3):399-408
pubmed: 22304911
Clin Cancer Res. 2013 Jan 1;19(1):138-47
pubmed: 23166225
Cancer Res. 2008 Oct 15;68(20):8635-42
pubmed: 18922940
Oncol Lett. 2012 May;3(5):1011-1016
pubmed: 22783382
Clin Orthop Relat Res. 2008 Sep;466(9):2052-9
pubmed: 18528739
Proc Natl Acad Sci U S A. 2014 Dec 23;111(51):E5564-73
pubmed: 25512523
J Bone Oncol. 2016 Jan 28;5(1):22-9
pubmed: 26998423
Diagn Pathol. 2014 Nov 29;9:221
pubmed: 25432701
Methods Mol Biol. 2012;874:1-20
pubmed: 22528435
Mol Cancer Ther. 2016 Oct;15(10):2465-2474
pubmed: 27507852
Ann Oncol. 2016 Apr;27(4):738-44
pubmed: 26787232
J Natl Cancer Inst. 2007 Oct 3;99(19):1441-54
pubmed: 17895480
Onco Targets Ther. 2016 Mar 14;9:1477-87
pubmed: 27042116
Clin Cancer Res. 2000 Feb;6(2):572-7
pubmed: 10690541
Histopathology. 2015 Sep;67(3):368-77
pubmed: 25641082
Pediatr Blood Cancer. 2012 Dec 15;59(7):1215-22
pubmed: 22544557
J Biochem Mol Toxicol. 2007;21(5):273-9
pubmed: 17912702
Cancer Res. 2010 Nov 1;70(21):8651-61
pubmed: 20959468
Cancer Res. 2006 Jan 1;66(1):221-31
pubmed: 16397235
N Engl J Med. 2010 Feb 4;362(5):387-401
pubmed: 20089952
Oncol Lett. 2019 Aug;18(2):1259-1266
pubmed: 31423186
Lancet Oncol. 2016 Oct;17(10):1396-1408
pubmed: 27569442
Chin J Cancer Res. 2017 Oct;29(5):447-454
pubmed: 29142464
Curr Mol Pharmacol. 2010 Jun;3(2):53-65
pubmed: 20302564