Orchidaceae-Derived Anticancer Agents: A Review.
anticancer
orchids
secondary metabolites
Journal
Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829
Informations de publication
Date de publication:
31 Jan 2022
31 Jan 2022
Historique:
received:
30
12
2021
revised:
28
01
2022
accepted:
28
01
2022
entrez:
15
2
2022
pubmed:
16
2
2022
medline:
16
2
2022
Statut:
epublish
Résumé
Species of orchids, which belong to the largest family of flowering plants, are commonly used in folk medicine for the treatment of infections and tumors. However, little is known about the actual chemical composition of these plants and their anticancer properties. In this paper, the most recent literature on orchid-derived bioactive substances with anticancer properties is reviewed. For the assessment, previous papers on the anticancer activity of Orchidaceae published since 2015 were considered. The papers were found by exploring electronic databases. According to the available data, many species of orchids contain potential antitumor chemicals. The bioactive substances in a relatively insignificant number of orchids are identified, and most studies are on Asian taxa. Broader research on American and African species and the correct identification of samples included in the experiments are essential for evaluating the usefulness of orchids as a plant family with vast anticancer potential.
Identifiants
pubmed: 35159021
pii: cancers14030754
doi: 10.3390/cancers14030754
pmc: PMC8833831
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Subventions
Organisme : Ministry of Education, Youth and Sports of CR
ID : LM2018123
Références
Fitoterapia. 2017 Oct;122:76-79
pubmed: 28844931
J Asian Nat Prod Res. 2019 Dec;21(12):1170-1176
pubmed: 30585518
J Ethnopharmacol. 2014 Dec 2;158 Pt B:495-7
pubmed: 25281419
Nat Prod Commun. 2016 May;11(5):657-9
pubmed: 27319143
Plant Signal Behav. 2019;14(1):1552056
pubmed: 30507332
J Asian Nat Prod Res. 2020 Jan;22(1):83-90
pubmed: 30450973
QJM. 2005 Sep;98(9):625-31
pubmed: 16006500
J Asian Nat Prod Res. 2016 Dec;18(12):1143-1150
pubmed: 27311018
Chem Biodivers. 2017 Nov;14(11):
pubmed: 28771984
Int J Environ Res Public Health. 2020 May 12;17(10):
pubmed: 32408690
J Nat Prod. 2001 Aug;64(8):1084-6
pubmed: 11520233
Zhongguo Zhong Yao Za Zhi. 2005 Mar;30(5):353-6
pubmed: 15806968
Med Princ Pract. 2005;14 Suppl 1:35-48
pubmed: 16103712
Fitoterapia. 2020 Jul;144:104607
pubmed: 32387373
Br J Pharmacol. 2020 Mar;177(6):1409-1423
pubmed: 31368509
Sci Rep. 2021 Jan 14;11(1):1424
pubmed: 33446865
Cell Mol Biol (Noisy-le-grand). 2018 Jun 25;64(8):35-43
pubmed: 29981681
Fitoterapia. 2020 Apr;142:104497
pubmed: 32058054
Food Nutr Res. 2019 Sep 06;63:
pubmed: 31548837
Mol Med Rep. 2017 Mar;15(3):1195-1203
pubmed: 28138710
3 Biotech. 2021 Dec;11(12):507
pubmed: 34868802
Plant Divers. 2018 Jun 25;40(4):196-208
pubmed: 30740565
J Ethnopharmacol. 2021 Apr 24;270:113851
pubmed: 33485987
Biol Rev Camb Philos Soc. 2006 May;81(2):219-35
pubmed: 16677433
J Comp Physiol A. 2000 Jun;186(6):567-74
pubmed: 10947239
Proc Biol Sci. 2003 Mar 7;270(1514):517-22
pubmed: 12641907
Front Pharmacol. 2018 Aug 02;9:807
pubmed: 30116189
New Phytol. 2018 Sep;219(4):1207-1215
pubmed: 29790578
Fitoterapia. 2019 Oct;138:104313
pubmed: 31421147
Int J Mol Sci. 2018 May 07;19(5):
pubmed: 29735884
Biomed Pharmacother. 2019 Feb;110:371-379
pubmed: 30529770
Heliyon. 2020 May 17;6(5):e03991
pubmed: 32455176
Anticancer Res. 2018 Nov;38(11):6281-6290
pubmed: 30396948
Phytochemistry. 2017 May;137:132-138
pubmed: 28215606
Chem Cent J. 2018 Sep 25;12(1):100
pubmed: 30255241
CA Cancer J Clin. 2021 May;71(3):209-249
pubmed: 33538338
New Phytol. 2017 Jul;215(2):891-905
pubmed: 28631324
Nat Prod Res. 2017 Jul;31(13):1518-1522
pubmed: 28278646
Fitoterapia. 2016 Dec;115:96-100
pubmed: 27720924
Drug Des Devel Ther. 2019 Jul 29;13:2591-2601
pubmed: 31551653
Fitoterapia. 2015 Jun;103:27-32
pubmed: 25759120
Drug Resist Updat. 2010 Aug-Oct;13(4-5):109-18
pubmed: 20692200
Antioxidants (Basel). 2016 Sep 14;5(3):
pubmed: 27649250
Nat Prod Res. 2020 Dec 21;:1-12
pubmed: 33342306
J Nat Prod. 2018 Feb 23;81(2):227-235
pubmed: 29338260
Evid Based Complement Alternat Med. 2016;2016:1213090
pubmed: 28119756
Oncol Lett. 2018 Apr;15(4):4611-4618
pubmed: 29541233
J Chromatogr B Analyt Technol Biomed Life Sci. 2020 Mar 1;1140:122017
pubmed: 32050157
Org Biomol Chem. 2019 Jan 16;17(3):567-572
pubmed: 30574990
Ann Bot. 2002 Oct;90(4):477-84
pubmed: 12324271
Zhongguo Zhong Yao Za Zhi. 2005 Jul;30(14):1053-61
pubmed: 16161436
Curr Med Chem Anticancer Agents. 2002 Mar;2(2):209-14
pubmed: 12678744
BMC Complement Altern Med. 2018 Apr 23;18(1):134
pubmed: 29685150
PLoS One. 2013;8(3):e58268
pubmed: 23472167
Recent Pat Drug Deliv Formul. 2010 Nov;4(3):231-44
pubmed: 20626333
Curr Microbiol. 2011 Apr;62(4):1218-24
pubmed: 21181405
Drug Des Devel Ther. 2020 Aug 12;14:3301-3313
pubmed: 32848368
PLoS One. 2015 Jan 20;10(1):e0115168
pubmed: 25602282
BMC Complement Altern Med. 2017 Dec 29;17(1):553
pubmed: 29284478
J Genet Eng Biotechnol. 2016 Jun;14(1):77-81
pubmed: 30647600
Zhongguo Zhong Yao Za Zhi. 2014 Feb;39(3):442-7
pubmed: 24946545
Biomedicines. 2021 Aug 03;9(8):
pubmed: 34440158
Signal Transduct Target Ther. 2020 May 8;5(1):51
pubmed: 32382060
Int J Mol Sci. 2018 May 23;19(6):
pubmed: 29882900
Expert Rev Clin Pharmacol. 2016 Jul;9(7):905-15
pubmed: 27070431
Ann N Y Acad Sci. 2017 Aug;1401(1):19-27
pubmed: 28891091
Int J Biol Macromol. 2018 Jun;112:921-928
pubmed: 29432833
J Nat Prod. 2018 Mar 23;81(3):661-678
pubmed: 29280630
Biotechnol Lett. 2015 Jul;37(7):1325-34
pubmed: 25792513
J Ethnopharmacol. 2014 Mar 28;152(3):387-92
pubmed: 24321863
Molecules. 2019 Jul 17;24(14):
pubmed: 31319503
Am J Chin Med. 2014;42(6):1539-54
pubmed: 25427623
Nat Prod Res. 2021 Dec;35(23):4916-4921
pubmed: 32208851
J Soc Integr Oncol. 2008 Fall;6(4):150-7
pubmed: 19134447
Am J Bot. 2002 Nov;89(11):1852-8
pubmed: 21665614
Int J Mol Sci. 2015 Sep 11;16(9):21975-88
pubmed: 26378526
Plants (Basel). 2020 Jun 22;9(6):
pubmed: 32580487
Biomed Pharmacother. 2016 Dec;84:1419-1427
pubmed: 27802902
PhytoKeys. 2016 Jul 08;(65):113-24
pubmed: 27489492
PLoS One. 2016 Jan 11;11(1):e0146880
pubmed: 26752741
Anticancer Res. 2020 Sep;40(9):4989-4999
pubmed: 32878787
J R Soc Med. 2007 Dec;100(12):558-63
pubmed: 18065708
J Ethnopharmacol. 2014 Dec 2;158 Pt B:449-53
pubmed: 25086408
Nat Prod Res. 2018 Jul;32(14):1699-1705
pubmed: 29092642
Med J Aust. 1970 Dec 26;2(26):1259-61
pubmed: 4939068
Biochim Biophys Acta. 2016 Dec;1866(2):266-275
pubmed: 27717733
Biomolecules. 2019 Sep 12;9(9):
pubmed: 31547263
Phytomedicine. 2017 Jan 15;24:157-165
pubmed: 28160857
Molecules. 2019 Jan 02;24(1):
pubmed: 30609689
Evid Based Complement Alternat Med. 2015;2015:767136
pubmed: 26421052
J Nat Med. 2018 Mar;72(2):503-513
pubmed: 29426985
PhytoKeys. 2021 Nov 29;186:11-41
pubmed: 34949955
Am J Bot. 2012 Oct;99(10):1655-65
pubmed: 23032816
Front Chem. 2019 Nov 29;7:812
pubmed: 31850306
New Phytol. 1997 Jan;135(1):143-149
pubmed: 33863156
Evid Based Complement Alternat Med. 2016;2016:4561674
pubmed: 27651818
Anticancer Res. 2015 Jan;35(1):201-5
pubmed: 25550552
Anticancer Agents Med Chem. 2012 Dec;12(10):1281-305
pubmed: 22583408
Molecules. 2016 Oct 27;21(11):
pubmed: 27801800
Biochem Genet. 2014 Apr;52(3-4):127-36
pubmed: 24213846
J Complement Integr Med. 2017 Jun 1;14(2):
pubmed: 28195549
Ecology. 2006 Apr;87(4):903-11
pubmed: 16676534
Cancer. 2002 Jul 1;95(1):155-63
pubmed: 12115329
Onco Targets Ther. 2019 Jul 09;12:5457-5465
pubmed: 31371985
Nat Prod Res. 2020 Feb;34(3):323-328
pubmed: 30580630
J Agric Food Chem. 2019 Jul 3;67(26):7274-7280
pubmed: 31244200
Phytomedicine. 2019 Feb;53:18-27
pubmed: 30668397
PLoS One. 2017 Sep 25;12(9):e0185021
pubmed: 28945763
Fitoterapia. 2016 Dec;115:15-18
pubmed: 27642042
Apoptosis. 2015 Dec;20(12):1531-62
pubmed: 26362468
Fitoterapia. 2020 Jun;143:104586
pubmed: 32247772
Nat Prod Commun. 2016 Apr;11(4):477-9
pubmed: 27396197
Proc Biol Sci. 2011 Feb 22;278(1705):554-9
pubmed: 20610425
Onco Targets Ther. 2015 Dec 21;9:21-30
pubmed: 26730200
Pharmacogn Rev. 2012 Jan;6(11):1-5
pubmed: 22654398
J Nat Prod. 2003 Jul;66(7):1022-37
pubmed: 12880330
Curr Opin Plant Biol. 2016 Aug;32:37-46
pubmed: 27368084
Molecules. 2016 Aug 19;21(8):
pubmed: 27548132
J Nat Med. 2018 Jan;72(1):246-251
pubmed: 29063360
Mycorrhiza. 2020 Jan;30(1):5-22
pubmed: 31982950
Bioengineered. 2019 Dec;10(1):316-334
pubmed: 31347943
Evid Based Complement Alternat Med. 2015;2015:350410
pubmed: 25685168
Planta Med. 2006 Oct;72(13):1244-7
pubmed: 16981129
Anticancer Res. 2017 Nov;37(11):6281-6289
pubmed: 29061811
Phytochemistry. 2021 Feb;182:112609
pubmed: 33326906
Front Plant Sci. 2021 May 07;12:646325
pubmed: 34025694
Chem Biodivers. 2021 May;18(5):e2001023
pubmed: 33721383
J Ethnopharmacol. 2017 Sep 14;209:184-202
pubmed: 28755972
Fitoterapia. 2009 Oct;80(7):381-4
pubmed: 19446615
J Asian Nat Prod Res. 2008 May-Jun;10(5-6):453-7
pubmed: 18464086
Molecules. 2016 Nov 23;21(11):
pubmed: 27886100
Evid Based Complement Alternat Med. 2015;2015:836564
pubmed: 26339272
Plant Biol (Stuttg). 2020 Jul;22(4):555-561
pubmed: 32181557
Zhongguo Zhong Yao Za Zhi. 2014 Mar;39(5):851-6
pubmed: 25204178
J Asian Nat Prod Res. 2011 Mar;13(3):251-5
pubmed: 21409687
Nat Prod Res. 2017 May;31(9):1042-1046
pubmed: 27931121
Phytomedicine. 2019 Sep;62:152932
pubmed: 31100681
Chin J Nat Med. 2020 Feb;18(2):81-89
pubmed: 32172951
Front Pharmacol. 2014 Jan 10;4:177
pubmed: 24454289
J Zhejiang Univ Sci B. 2013 Sep;14(9):785-92
pubmed: 24009198
Dose Response. 2021 Mar 15;19(1):15593258211001251
pubmed: 33795998
Evid Based Complement Alternat Med. 2013;2013:302426
pubmed: 23956768
Sci Rep. 2021 Feb 9;11(1):3439
pubmed: 33564041