Three Months of Strength Training Changes the Gene Expression of Inflammation-Related Genes in PBMC of Older Women: A Randomized Controlled Trial.
aged
gene expression
inflammation
leukocytes
resistance training
Journal
Cells
ISSN: 2073-4409
Titre abrégé: Cells
Pays: Switzerland
ID NLM: 101600052
Informations de publication
Date de publication:
03 02 2022
03 02 2022
Historique:
received:
06
10
2021
revised:
19
01
2022
accepted:
01
02
2022
entrez:
15
2
2022
pubmed:
16
2
2022
medline:
9
4
2022
Statut:
epublish
Résumé
Here, we investigate changes in inflammation-related gene-expression in peripheral mononuclear blood cells (PBMC) by strength training. A total of 14 women aged ≥65 years were randomized into 3 months of either 3×/week intensive strength training (IST: 3×10 rep at 80% 1RM), strength endurance training (SET: 2×30 reps at 40% 1RM) or control (CON: 3×30 sec stretching). Differentially expressed genes (fold change ≤0.67 or ≥1.5) were identified by targeted RNA-sequencing of 407 inflammation-related genes. A total of 98 genes (
Identifiants
pubmed: 35159340
pii: cells11030531
doi: 10.3390/cells11030531
pmc: PMC8834561
pii:
doi:
Substances chimiques
Triggering Receptor Expressed on Myeloid Cells-1
0
Types de publication
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Research Foundation - Flanders
ID : G074221N
Organisme : Vrije Universiteit Brussel
ID : SRP
Organisme : Wetenschappelijk Fonds Willy Gepts
ID : WFWG20-02
Références
J Psychiatr Res. 1975 Nov;12(3):189-98
pubmed: 1202204
J Leukoc Biol. 2005 Oct;78(4):819-35
pubmed: 16033812
J Appl Physiol (1985). 2019 Apr 1;126(4):894-902
pubmed: 30605403
Exerc Immunol Rev. 2006;12:6-33
pubmed: 17201070
Gerontology. 2005 Jul-Aug;51(4):253-65
pubmed: 15980654
Exp Mol Med. 2017 Nov 24;49(11):e402
pubmed: 29170475
Eur J Appl Physiol. 2011 Dec;111(12):2919-29
pubmed: 21437602
Physiol Rev. 2000 Jul;80(3):1055-81
pubmed: 10893431
J Nutr Health Aging. 2018;22(10):1148-1161
pubmed: 30498820
Front Physiol. 2021 Aug 20;12:668327
pubmed: 34489717
Behav Res Methods. 2009 Nov;41(4):1149-60
pubmed: 19897823
Clin Genet. 2013 Nov;84(5):489-95
pubmed: 23414114
Nature. 1997 Feb 13;385(6617):640-4
pubmed: 9024663
Exp Gerontol. 2017 Jul;93:46-53
pubmed: 28433473
Eur J Appl Physiol. 2017 Mar;117(3):511-519
pubmed: 28168555
Exerc Immunol Rev. 2013;19:29-48
pubmed: 23977718
Scand J Infect Dis. 2003;35(9):573-6
pubmed: 14620137
Exp Gerontol. 2004 May;39(5):687-99
pubmed: 15130663
Atherosclerosis. 2010 Oct;212(2):668-73
pubmed: 20723894
Scand J Med Sci Sports. 2003 Feb;13(1):56-62
pubmed: 12535318
J Appl Physiol (1985). 2004 Oct;97(4):1461-9
pubmed: 15194674
FASEB J. 2003 May;17(8):884-6
pubmed: 12626436
Mech Ageing Dev. 2008 Jun;129(6):313-21
pubmed: 18377953
Exp Gerontol. 2021 Apr;146:111236
pubmed: 33453323
Genome Biol. 2014;15(12):550
pubmed: 25516281
J Leukoc Biol. 1992 Sep;52(3):303-6
pubmed: 1522389
Curr Opin Clin Nutr Metab Care. 2017 Jan;20(1):30-53
pubmed: 27755209
Front Physiol. 2020 Oct 16;11:582258
pubmed: 33178046
Front Immunol. 2014 Sep 25;5:461
pubmed: 25309543
J Cell Biochem. 2019 Apr;120(4):5333-5342
pubmed: 30324630
J Leukoc Biol. 2001 May;69(5):747-54
pubmed: 11358983
Exp Physiol. 2013 Mar;98(3):778-83
pubmed: 23143992
Age Ageing. 2019 Jan 1;48(1):16-31
pubmed: 30312372
Exp Gerontol. 2015 Sep;69:159-69
pubmed: 25981742
Eur J Appl Physiol. 2011 Jun;111(6):1035-45
pubmed: 21088973
Physiol Rev. 2008 Oct;88(4):1379-406
pubmed: 18923185
Brain Behav Immun. 2014 Jul;39:130-41
pubmed: 24513876
Br J Sports Med. 2010 Mar;44(4):232-7
pubmed: 18499764
Sports Med. 2015 Dec;45(12):1693-720
pubmed: 26420238
Arthritis Res Ther. 2021 Jul 10;23(1):187
pubmed: 34246305
J Neuroinflammation. 2016 Nov 10;13(1):289
pubmed: 27832807
Exp Physiol. 2011 Jun;96(6):590-8
pubmed: 21421702
J Cell Mol Med. 2017 Jan;21(1):154-164
pubmed: 27599751
Bull Exp Biol Med. 2012 Oct;153(6):866-8
pubmed: 23113305
Am J Physiol. 1996 Jul;271(1 Pt 2):R222-7
pubmed: 8760224
Front Immunol. 2021 Apr 16;12:639308
pubmed: 33936054
J Appl Physiol (1985). 2010 Apr;108(4):769-79
pubmed: 20368384
BMC Cardiovasc Disord. 2018 Jul 3;18(1):137
pubmed: 29969989
Physiol Rep. 2015 Aug;3(8):
pubmed: 26272733
J Nutr Health Aging. 2019;23(6):494-502
pubmed: 31233069
J Appl Physiol (1985). 2005 Apr;98(4):1154-62
pubmed: 15772055
J Appl Physiol (1985). 1997 May;82(5):1385-94
pubmed: 9134882
Eur J Appl Physiol. 2011 Jul;111(7):1351-9
pubmed: 21153418
Age (Dordr). 2014;36(5):9704
pubmed: 25128203
Ageing Res Rev. 2017 Jul;36:1-10
pubmed: 28223244
J Aging Res. 2018 Oct 28;2018:1467025
pubmed: 30510801
Exp Mol Med. 2015 Apr 03;47:e156
pubmed: 25838003
Front Physiol. 2021 Aug 24;12:715044
pubmed: 34504439
BMC Geriatr. 2004 Jul 23;4:6
pubmed: 15272934
J Gerontol A Biol Sci Med Sci. 2019 Nov 13;74(12):1870-1878
pubmed: 30285092
Biol Chem. 2001 Jan;382(1):5-14
pubmed: 11258672
Bull Exp Biol Med. 2009 Mar;147(3):361-5
pubmed: 19529862
Exp Gerontol. 2021 Jul 1;149:111318
pubmed: 33794319
FASEB J. 2003 Nov;17(14):2166-8
pubmed: 12958150
J Geriatr Phys Ther. 2007;30(2):49-52
pubmed: 18171487
Nutrients. 2021 Feb 19;13(2):
pubmed: 33669497
Nat Med. 2003 Feb;9(2):213-9
pubmed: 12524534
J Am Med Dir Assoc. 2016 Jun 1;17(6):547-52
pubmed: 27052561
Physiol Genomics. 2011 Jul 27;43(14):895-902
pubmed: 21610086
Med Sci Sports Exerc. 1993 May;25(5):628-42
pubmed: 8492692
Cells. 2021 Apr 08;10(4):
pubmed: 33917916
Exerc Immunol Rev. 2002;8:6-48
pubmed: 12690937
Scand J Med Sci Sports. 2015 Dec;25 Suppl 3:1-72
pubmed: 26606383