Diminished Endothelial Function but Normal Vascular Structure in Adults with Tetralogy of Fallot.
EndoPAT
carotid intima-media thickness
endothelium
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
19 Jan 2022
19 Jan 2022
Historique:
received:
29
11
2021
revised:
01
01
2022
accepted:
14
01
2022
entrez:
15
2
2022
pubmed:
16
2
2022
medline:
16
2
2022
Statut:
epublish
Résumé
The life expectancy of patients with Tetralogy of Fallot (ToF) has increased in recent years. As a result, other risk factors with later onset in life are in the focus of patient care. Endothelial function is an early indicator of cardiovascular risk and was investigated along further structural vessel properties. A total of 17 patients (41.7 ± 7.1 years, 8 women) with Tetralogy of Fallot were 1:2 matched for sex with 34 (38.9 ± 8.1 years, 16 women) healthy volunteers. Participants received an assessment of their endothelial function and a structural assessment of the aorta. Patients with ToF showed a reduced endothelial function determined by reactive hyperaemia index after adjusting for age, weight and height (ToF: 1.55 ± 0.31 vs. controls: 1.84 ± 0.47;
Identifiants
pubmed: 35159945
pii: jcm11030493
doi: 10.3390/jcm11030493
pmc: PMC8836741
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Kinderherzen Fördergemeinschaft Deutsche Kinderherzzentren e.V
ID : W-M-025/2017
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