Associated Factors of High Sedative Requirements within Patients with Moderate to Severe COVID-19 ARDS.
acute respiratory distress syndrome
critical care
hypnotics and sedatives
prone position
pulmonary ventilation
severe acute respiratory syndrome coronavirus 2
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
25 Jan 2022
25 Jan 2022
Historique:
received:
25
11
2021
revised:
16
01
2022
accepted:
19
01
2022
entrez:
15
2
2022
pubmed:
16
2
2022
medline:
16
2
2022
Statut:
epublish
Résumé
The coronavirus pandemic continues to challenge global healthcare. Severely affected patients are often in need of high doses of analgesics and sedatives. The latter was studied in critically ill coronavirus disease 2019 (COVID-19) patients in this prospective monocentric analysis. COVID-19 acute respiratory distress syndrome (ARDS) patients admitted between 1 April and 1 December 2020 were enrolled in the study. A statistical analysis of impeded sedation using mixed-effect linear regression models was performed. Overall, 114 patients were enrolled, requiring unusual high levels of sedatives. During 67.9% of the observation period, a combination of sedatives was required in addition to continuous analgesia. During ARDS therapy, 85.1% (
Identifiants
pubmed: 35160040
pii: jcm11030588
doi: 10.3390/jcm11030588
pmc: PMC8837042
pii:
doi:
Types de publication
Journal Article
Langues
eng
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