Molecular Features and Clinical Management of Hereditary Pancreatic Cancer Syndromes and Familial Pancreatic Cancer.
PARP inhibitor
familial pancreatic cancer
germline mutation
hereditary pancreatic cancer syndrome
loss of heterozygosity
surveillance
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
21 Jan 2022
21 Jan 2022
Historique:
received:
23
12
2021
revised:
16
01
2022
accepted:
18
01
2022
entrez:
15
2
2022
pubmed:
16
2
2022
medline:
5
3
2022
Statut:
epublish
Résumé
Hereditary pancreatic cancers are caused by several inherited genes. Familial pancreatic cancer is defined as pancreatic cancer arising in a patient with at least two first-degree relatives with pancreatic cancer in the absence of an identified genetic cause. Hereditary pancreatic cancer syndromes and familial pancreatic cancers account for about 10% of pancreatic cancer cases. Germline mutations in
Identifiants
pubmed: 35163129
pii: ijms23031205
doi: 10.3390/ijms23031205
pmc: PMC8835700
pii:
doi:
Substances chimiques
Biomarkers, Tumor
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
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