Functional side-to-side splenorenal shunts to treat extrahepatic portal vein thrombosis in children.


Journal

American journal of surgery
ISSN: 1879-1883
Titre abrégé: Am J Surg
Pays: United States
ID NLM: 0370473

Informations de publication

Date de publication:
07 2022
Historique:
received: 28 10 2021
revised: 16 12 2021
accepted: 30 01 2022
pubmed: 16 2 2022
medline: 28 6 2022
entrez: 15 2 2022
Statut: ppublish

Résumé

Surgical shunts are commonly used to manage complications resulting from extrahepatic portal vein thrombosis (EHPVT) in children. We describe a single-center experience utilizing a functional Side-to-Side Splenorenal Shunt (fSRS), created using either an enlarged inferior mesenteric vein (IMV) or left adrenal vein (LAV). Pediatric patients with isolated EHPVT who were poor candidates for a Rex shunt and who underwent a fSRS procedure at our institution between 2003 and 2020 were reviewed. The pre/post shunt portosystemic gradient change, rates of early and late complications, postoperative shunt patency, and mortality were evaluated. Twelve EHPVT patients (mean age of 6.1 years) underwent a fSRS procedure. The mean portosystemic gradient change for the cohort was -11.7 mmHg (±4.9). There were no cases of recurrent variceal bleeding or episodes of shunt thrombosis reported after fSRS procedures. Surgical shunts continue to be an important adjunct in the treatment of complications related to EHPVT. The functional Side-to-Side Splenorenal Shunt is a safe alternative that is easy to perform, involves minimal dissection and requires only a single anastomosis.

Sections du résumé

BACKGROUND
Surgical shunts are commonly used to manage complications resulting from extrahepatic portal vein thrombosis (EHPVT) in children. We describe a single-center experience utilizing a functional Side-to-Side Splenorenal Shunt (fSRS), created using either an enlarged inferior mesenteric vein (IMV) or left adrenal vein (LAV).
METHODS
Pediatric patients with isolated EHPVT who were poor candidates for a Rex shunt and who underwent a fSRS procedure at our institution between 2003 and 2020 were reviewed. The pre/post shunt portosystemic gradient change, rates of early and late complications, postoperative shunt patency, and mortality were evaluated.
RESULTS
Twelve EHPVT patients (mean age of 6.1 years) underwent a fSRS procedure. The mean portosystemic gradient change for the cohort was -11.7 mmHg (±4.9). There were no cases of recurrent variceal bleeding or episodes of shunt thrombosis reported after fSRS procedures.
CONCLUSIONS
Surgical shunts continue to be an important adjunct in the treatment of complications related to EHPVT. The functional Side-to-Side Splenorenal Shunt is a safe alternative that is easy to perform, involves minimal dissection and requires only a single anastomosis.

Identifiants

pubmed: 35164959
pii: S0002-9610(22)00055-1
doi: 10.1016/j.amjsurg.2022.01.031
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

530-534

Informations de copyright

Copyright © 2022 Elsevier Inc. All rights reserved.

Auteurs

Alexander Y Yang (AY)

Department of Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.

Brianna L Slatnick (BL)

Department of Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.

Jonathan Durgin (J)

Department of Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.

Paul Truche (P)

Program in Global Surgery and Social Change, Harvard Medical School, Boston, MA, USA.

Heung Bae Kim (HB)

Department of Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.

Alex G Cuenca (AG)

Department of Surgery, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: alex.cuenca@childrens.harvard.edu.

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Classifications MeSH