Hashimoto's Thyroiditis Presents as an Acute Encephalopathy: A Case Report of Unusual Presentation.
altered mental state
autoimmune encephalitis
encephalopathy
hashimoto's thyroiditis
thyroid peroxidase antibody
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
Jan 2022
Jan 2022
Historique:
accepted:
11
01
2022
entrez:
15
2
2022
pubmed:
16
2
2022
medline:
16
2
2022
Statut:
epublish
Résumé
Hashimoto's thyroiditis is the most common thyroid disorder in the United States. Hashimoto encephalopathy is a rare presentation of Hashimoto's thyroiditis that is frequently misdiagnosed. We present the case of a 71-year-old female who had normal mental status at baseline. She presented with acute alteration in mental status. Further evaluation with brain MRI showed a hyperintense signal in the bilateral centrum. Spinal fluid analysis revealed elevated protein. Thyroid peroxidase (TPO) antibody was elevated at 59.7 and TSH was elevated at 4.9. Her mental status improved dramatically after treatment with steroids and levothyroxine. This diagnosis should be suspected when the patient develops acute encephalopathy with positive serum thyroid antibody settings with a complete return to normal mental status after treatment with steroids.
Identifiants
pubmed: 35165583
doi: 10.7759/cureus.21130
pmc: PMC8831211
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e21130Informations de copyright
Copyright © 2022, Khatib et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
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