Semi-classical Monte Carlo algorithm for the simulation of X-ray grating interferometry.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
15 02 2022
Historique:
received: 22 09 2021
accepted: 12 01 2022
entrez: 16 2 2022
pubmed: 17 2 2022
medline: 17 2 2022
Statut: epublish

Résumé

Traditional simulation techniques such as wave optics methods and Monte Carlo (MC) particle transport cannot model both interference and inelastic scattering phenomena within one framework. Based on the rules of quantum mechanics to calculate probabilities, we propose a new semi-classical MC algorithm for efficient and simultaneous modeling of scattering and interference processes. The similarities to MC particle transport allow the implementation as a flexible c++ object oriented extension of EGSnrc-a well-established MC toolkit. In addition to previously proposed Huygens principle based transport through optics components, new variance reduction techniques for the transport through gratings are presented as transport options to achieve the required improvement in speed and memory costs necessary for an efficient exploration (system design-dose estimations) of the medical implementation of X-ray grating interferometry (GI), an emerging imaging technique currently subject of tremendous efforts towards clinical translation. The feasibility of simulation of interference effects is confirmed in four academic cases and an experimental table-top GI setup. Comparison with conventional MC transport show that deposited energy features of EGSnrc are conserved.

Identifiants

pubmed: 35169138
doi: 10.1038/s41598-022-05965-7
pii: 10.1038/s41598-022-05965-7
pmc: PMC8847374
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2485

Informations de copyright

© 2022. The Author(s).

Références

Opt Express. 2014 Sep 22;22(19):23480-8
pubmed: 25321817
Opt Express. 2005 Aug 8;13(16):6296-304
pubmed: 19498642
Med Phys. 2012 Jul;39(7):4467-82
pubmed: 22830779
Opt Express. 2021 Jan 18;29(2):2049-2064
pubmed: 33726406
Phys Rev Lett. 2012 Apr 13;108(15):158102
pubmed: 22587288
Med Phys. 2001 Aug;28(8):1610-9
pubmed: 11548930
Z Med Phys. 2013 Sep;23(3):176-85
pubmed: 23453793
Opt Express. 2005 Mar 21;13(6):2182-95
pubmed: 19495106
Rev Sci Instrum. 2014 May;85(5):053702
pubmed: 24880377
Sci Rep. 2019 Nov 26;9(1):17537
pubmed: 31772186
Invest Radiol. 2011 Dec;46(12):801-6
pubmed: 21788904
Opt Express. 2020 Oct 26;28(22):33390-33412
pubmed: 33115004
J Synchrotron Radiat. 2014 May;21(Pt 3):613-22
pubmed: 24763652
Appl Opt. 2013 Oct 1;52(28):6940-7
pubmed: 24085208
Microscopy (Oxf). 2017 Jun 1;66(3):155-166
pubmed: 28430991
J Opt Soc Am A Opt Image Sci Vis. 2008 Oct;25(10):2571-81
pubmed: 18830335
J Am Stat Assoc. 1949 Sep;44(247):335-41
pubmed: 18139350
Nat Mater. 2008 Feb;7(2):134-7
pubmed: 18204454

Auteurs

Stefan Tessarini (S)

Institute for Biomedical Engineering, University and ETH Zürich, 8092, Zürich, Switzerland. stefan.tessarini@psi.ch.
Swiss Light Source, Paul Scherrer Institut, 5232, Villigen, Switzerland. stefan.tessarini@psi.ch.

Michael Karl Fix (MK)

Division of Medical Radiation Physics and Department of Radiation Oncology, Inselspital University Hospital Bern and University of Bern, Bern, Switzerland.

Peter Manser (P)

Division of Medical Radiation Physics and Department of Radiation Oncology, Inselspital University Hospital Bern and University of Bern, Bern, Switzerland.

Werner Volken (W)

Division of Medical Radiation Physics and Department of Radiation Oncology, Inselspital University Hospital Bern and University of Bern, Bern, Switzerland.

Daniel Frei (D)

Division of Medical Radiation Physics and Department of Radiation Oncology, Inselspital University Hospital Bern and University of Bern, Bern, Switzerland.

Lorenzo Mercolli (L)

Federal Office of Public Health FOPH, Schwarzenburgstrasse 157, 3003, Bern, Switzerland.
Laboratory for High Energy Physics, University of Bern, Sidlerstrasse 5, 3011, Bern, Switzerland.

Marco Stampanoni (M)

Institute for Biomedical Engineering, University and ETH Zürich, 8092, Zürich, Switzerland.
Swiss Light Source, Paul Scherrer Institut, 5232, Villigen, Switzerland.

Classifications MeSH