TRASS: a global approach to assess the severity of truncal acne.


Journal

Journal of the European Academy of Dermatology and Venereology : JEADV
ISSN: 1468-3083
Titre abrégé: J Eur Acad Dermatol Venereol
Pays: England
ID NLM: 9216037

Informations de publication

Date de publication:
Jun 2022
Historique:
revised: 07 12 2021
received: 30 07 2021
accepted: 07 01 2022
pubmed: 17 2 2022
medline: 14 5 2022
entrez: 16 2 2022
Statut: ppublish

Résumé

Only a small amount of published data regarding truncal acne is available, and no proper tool to assess its severity exists. The aim of the study was to provide dermatologists with an easy-to-use tool to assess truncal acne (TRASS, truncal acne severity scale) using a global approach. A scoring tool that assesses the severity of acne (based on GEA and ECLA scales) on the trunk using a global approach was built, including three sub-scores: family history, clinical signs and quality of life (QoL). In order to test TRASS, the experts used photographs of 47 patients attending their clinics with truncal acne. The regression optimized (ROP) model was applied to assess the diagnosis performance of TRASS and to identify items contributing to the classification of the patients. Internal testing was made to demonstrate the robustness of the model. Correlation analyses between the different items were performed to evaluate the interaction between the different items and their impact on the severity grading of truncal acne. Patients with the most severe acne were identified by TRASS. The error level was 6.6% after internal validation and 10.4% when using the median value or the centile 75th (6.6% and 10.4%). Correlation was significant between systemic treatment and scars (P = 0.0025) and nodules (P = 0.01988) and between location and QoL (P = 0.0095). Truncal acne severity scale is the first global, patient-centred approach to evaluate truncal acne by scoring the importance of each factor independently from its clinical severity. TRASS may allow the practitioner to choose and validate the most suitable therapy together with the patient in order to treat his or her truncal acne successfully and to limit treatment failure.

Identifiants

pubmed: 35170810
doi: 10.1111/jdv.18009
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

897-904

Subventions

Organisme : Galderma International

Informations de copyright

© 2022 European Academy of Dermatology and Venereology.

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Auteurs

N Auffret (N)

Private Practice, Paris, France.

J M Nguyen (JM)

Biostatistic and Epidemiology, Inserm U1232, Nantes, France.

M-T Leccia (MT)

Department of Dermatology, Allergology and Photobiology, CHU A Michallon, Grenoble, France.

J P Claudel (JP)

Private Practice, Tours, France.

B Dréno (B)

UF dermato-cancérologie, CHU Nantes-Hôtel-Dieu, Inserm U1232, CIC Biothérapie Inserm 05031, Nantes, France.

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