Risk Factors for the Absence of Diagnosis of Asthma Despite Disease Symptoms: Results from the Swedish GA2LEN Study.
asthma symptoms
no diagnosis despite symptoms of asthma
Journal
Journal of asthma and allergy
ISSN: 1178-6965
Titre abrégé: J Asthma Allergy
Pays: New Zealand
ID NLM: 101543450
Informations de publication
Date de publication:
2022
2022
Historique:
received:
24
11
2021
accepted:
11
01
2022
entrez:
17
2
2022
pubmed:
18
2
2022
medline:
18
2
2022
Statut:
epublish
Résumé
Asthma is a common chronic disease presenting with airway symptoms such as wheezing, chest tightness and attacks of breathlessness. Underdiagnosis of asthma is common and correlates to negative outcomes such as a lower quality of life and reduced work capacity. This study aims to identify factors for not being diagnosed with asthma if presenting with asthma symptoms. A questionnaire was sent to 45,000 subjects (age 16-74 years) in Sweden. Subjects who reported both wheeze and breathlessness and wheeze when not having a cold were defined as having asthma-related symptoms. Data on demographics, educational level, smoking, physical activity, comorbidities, symptoms and asthma were collected. Logistic regression was used to identify risk factors for not being diagnosed with asthma. Of the 25,391 who responded to the survey, 6.2% reported asthma-related symptoms. Of these, 946 had been diagnosed with asthma previously, while 632 had not. Independent risk factors for not being diagnosed with asthma were higher age (OR (95% CI) (2.17 (1.39-3.40))), male sex (1.46 (1.17-1.81)), current smoking (2.92 (2.22-3.84)), low level of education (1.43 (1.01-2.01)), low physical activity (1.36 (1.06-1.74)), and hypertension (1.50 (1.06-2.12)). Men, smokers, older subjects, and those with low educational level or low physical activity are less likely to be diagnosed with asthma despite presenting asthma-related symptoms.
Sections du résumé
BACKGROUND
BACKGROUND
Asthma is a common chronic disease presenting with airway symptoms such as wheezing, chest tightness and attacks of breathlessness. Underdiagnosis of asthma is common and correlates to negative outcomes such as a lower quality of life and reduced work capacity.
PURPOSE
OBJECTIVE
This study aims to identify factors for not being diagnosed with asthma if presenting with asthma symptoms.
PATIENTS AND METHODS
METHODS
A questionnaire was sent to 45,000 subjects (age 16-74 years) in Sweden. Subjects who reported both wheeze and breathlessness and wheeze when not having a cold were defined as having asthma-related symptoms. Data on demographics, educational level, smoking, physical activity, comorbidities, symptoms and asthma were collected. Logistic regression was used to identify risk factors for not being diagnosed with asthma.
RESULTS
RESULTS
Of the 25,391 who responded to the survey, 6.2% reported asthma-related symptoms. Of these, 946 had been diagnosed with asthma previously, while 632 had not. Independent risk factors for not being diagnosed with asthma were higher age (OR (95% CI) (2.17 (1.39-3.40))), male sex (1.46 (1.17-1.81)), current smoking (2.92 (2.22-3.84)), low level of education (1.43 (1.01-2.01)), low physical activity (1.36 (1.06-1.74)), and hypertension (1.50 (1.06-2.12)).
CONCLUSION
CONCLUSIONS
Men, smokers, older subjects, and those with low educational level or low physical activity are less likely to be diagnosed with asthma despite presenting asthma-related symptoms.
Identifiants
pubmed: 35173449
doi: 10.2147/JAA.S350245
pii: 350245
pmc: PMC8842640
doi:
Types de publication
Journal Article
Langues
eng
Pagination
179-186Informations de copyright
© 2022 Kisiel et al.
Déclaration de conflit d'intérêts
The authors report no conflicts of interest in this work.
Références
Chest. 2002 Apr;121(4):1051-7
pubmed: 11948032
BMJ. 1998 Feb 28;316(7132):651-5; discussion 655-6
pubmed: 9522784
Allergy. 2013 Feb;68(2):213-9
pubmed: 23176562
Eur Respir J. 1998 Sep;12(3):557-63
pubmed: 9762779
Breathe (Sheff). 2019 Mar;15(1):e20-e27
pubmed: 31031841
Respir Med. 2014 Nov;108(11):1594-600
pubmed: 25282543
Am Rev Respir Dis. 1990 Dec;142(6 Pt 1):1367-71
pubmed: 2174657
J Asthma. 2015 Oct;52(8):823-30
pubmed: 25996179
Prim Care Respir J. 2008 Jun;17(2):79-89
pubmed: 18438594
Am J Respir Crit Care Med. 2018 Oct 15;198(8):1012-1020
pubmed: 29756989
Thorax. 2018 Apr;73(4):313-320
pubmed: 29074814
Allergy. 2009 Jul;64(7):969-77
pubmed: 19392994
Int Arch Allergy Immunol. 2011;155(4):403-11
pubmed: 21346371
Lancet. 2020 Oct 17;396(10258):1204-1222
pubmed: 33069326
CMAJ. 2008 Nov 18;179(11):1121-31
pubmed: 19015563
Respir Med. 2013 Nov;107(11):1651-8
pubmed: 24055634
Multidiscip Respir Med. 2012 Aug 08;7(1):24
pubmed: 22958936
ERJ Open Res. 2019 Feb 01;5(1):
pubmed: 30723731
Front Pediatr. 2019 Jun 18;7:246
pubmed: 31275909
Eur Respir J. 2008 Jan;31(1):143-78
pubmed: 18166595
Arch Intern Med. 1995 Nov 13;155(20):2225-8
pubmed: 7487245
Allergy. 2018 Feb;73(2):284-294
pubmed: 28722758
Curr Opin Pulm Med. 2012 Jan;18(1):57-62
pubmed: 22045347
PLoS One. 2011 Feb 17;6(2):e16082
pubmed: 21379386
Br J Gen Pract. 2002 Feb;52(475):132-4
pubmed: 11885822
Int Forum Allergy Rhinol. 2015 Sep;5 Suppl 1:S11-6
pubmed: 26335830
Postepy Dermatol Alergol. 2019 Feb;36(1):86-91
pubmed: 30858785
Sleep Med. 2006 Mar;7(2):123-30
pubmed: 16459140
Thorax. 2000 Jul;55(7):562-5
pubmed: 10856315
Eur Respir J. 1994 Dec;7(12):2146-53
pubmed: 7713195
Thorax. 2003 Oct;58(10):846-50
pubmed: 14514934
Respir Care. 2020 Feb;65(2):252-264
pubmed: 31662445