The use of lasers in vitiligo, an overview.
Journal
Journal of the European Academy of Dermatology and Venereology : JEADV
ISSN: 1468-3083
Titre abrégé: J Eur Acad Dermatol Venereol
Pays: England
ID NLM: 9216037
Informations de publication
Date de publication:
Jun 2022
Jun 2022
Historique:
revised:
10
12
2021
received:
04
08
2021
accepted:
03
02
2022
pubmed:
18
2
2022
medline:
14
5
2022
entrez:
17
2
2022
Statut:
ppublish
Résumé
Various types of lasers have been demonstrated to be effective in the treatment of vitiligo. The mode of action of these lasers is just as varied as the purpose of intervention. Many clinicians are not aware of the unique opportunity these lasers offer to improve the outcomes of vitiligo treatment. To date, no clear overview exists of the use of lasers in vitiligo treatment. Thus, the aim of this review is to discuss the various types of lasers and provide an overview of the evidence for their efficacy. We found good evidence from a systematic review that the excimer laser is effective, induces repigmentation rates comparable to NB-UVB and has improved outcomes when combined with calcineurin inhibitors. Ablative lasers are commonly used for tissue graft or melanocyte-keratinocyte cell graft transplantation. They provide safe, fast and uniform denudation of the epidermis with propitious repigmentation outcomes. We found conflicting evidence from two systematic reviews regarding the efficacy of fractional ablative lasers for improving outcomes of NB-UVB therapy, a systematic review including only fractional ablative lasers provided evidence for efficacy. Q-switched nanosecond lasers have shown to be safe and effective for inducing depigmentation, although recurrence is common, and most studies were small and retrospective. Despite proven efficacy and safety, laser treatments are relatively expensive and suited for limited body surface areas and selected cases. Each type of laser has benefits and risks associated and should, therefore, be individually chosen based on location, extent, activity and type of vitiligo.
Identifiants
pubmed: 35176186
doi: 10.1111/jdv.18005
pmc: PMC9314124
doi:
Types de publication
Journal Article
Review
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
779-789Informations de copyright
© 2022 The Authors. Journal of the European Academy of Dermatology and Venereology published by John Wiley & Sons Ltd on behalf of European Academy of Dermatology and Venereology.
Références
Photodermatol Photoimmunol Photomed. 2013 Feb;29(1):27-33
pubmed: 23281694
J Am Acad Dermatol. 2011 Aug;65(2):428-430
pubmed: 21763570
Lasers Surg Med. 2006 Mar;38(3):169-76
pubmed: 16532440
Am J Clin Dermatol. 2016 Feb;17(1):23-32
pubmed: 26520641
J Am Acad Dermatol. 2000 May;42(5 Pt 1):760-9
pubmed: 10775851
Lasers Surg Med. 2004;34(5):426-38
pubmed: 15216537
J Am Acad Dermatol. 2018 Mar;78(3):605-607.e1
pubmed: 28989105
J Dermatolog Treat. 2012 Apr;23(2):122-7
pubmed: 21254850
Br J Dermatol. 2012 Mar;166(3):658-61
pubmed: 22050270
Dermatol Surg. 2004 Jul;30(7):1043-5
pubmed: 15209798
Br J Dermatol. 2008 Nov;159(5):1186-91
pubmed: 18717675
Photodermatol Photoimmunol Photomed. 2021 Jan;37(1):74-77
pubmed: 32654300
Photomed Laser Surg. 2007 Oct;25(5):418-27
pubmed: 17975956
PLoS One. 2016 Sep 27;11(9):e0163806
pubmed: 27673680
J Eur Acad Dermatol Venereol. 2012 Jun;26(6):690-5
pubmed: 21711467
Arch Dermatol. 2004 Sep;140(9):1065-9
pubmed: 15381545
Br J Dermatol. 1977 Dec;97(6):669-79
pubmed: 603749
Br J Dermatol. 2005 May;152(5):981-5
pubmed: 15888156
J Eur Acad Dermatol Venereol. 2007 Apr;21(4):504-8
pubmed: 17373978
Br J Dermatol. 2010 Jul;163(1):188-92
pubmed: 20346025
J Am Acad Dermatol. 2017 Jul;77(1):17-29
pubmed: 28619557
Acta Derm Venereol. 1998 Mar;78(2):136-8
pubmed: 9534893
J Dtsch Dermatol Ges. 2018 Oct;16(10):1197-1208
pubmed: 30248232
Dermatol Surg. 2005 Apr;31(4):385-7
pubmed: 15871310
J Eur Acad Dermatol Venereol. 2014 Mar;28(3):374-7
pubmed: 23167541
J Dermatol. 2007 Jul;34(7):490-2
pubmed: 17584330
J Eur Acad Dermatol Venereol. 2017 Feb;31(2):337-340
pubmed: 27538097
J Cosmet Dermatol. 2019 Feb;18(1):142-149
pubmed: 29707867
Arch Dermatol. 2002 Dec;138(12):1619-20
pubmed: 12472364
Dermatol Surg. 2001 Nov;27(11):969-70
pubmed: 11737134
Plast Reconstr Surg. 1997 Jun;99(7):2089-94
pubmed: 9180739
Pediatr Dermatol. 2019 Jan;36(1):e53-e55
pubmed: 30520111
Lasers Surg Med. 2020 Sep;52(7):590-596
pubmed: 31820470
Br J Dermatol. 2012 Jan;166(1):208-11
pubmed: 21824124
Dermatol Surg. 1999 Nov;25(11):851-6
pubmed: 10594596
Lasers Surg Med. 2016 Feb;48(2):197-202
pubmed: 26175036
J Am Acad Dermatol. 2021 Jun;84(6):1619-1627
pubmed: 33508387
Arch Otolaryngol Head Neck Surg. 1997 Sep;123(9):929-34
pubmed: 9305242
Photodermatol Photoimmunol Photomed. 2006 Dec;22(6):310-4
pubmed: 17100739
Int J Dermatol. 2010 Mar;49(3):317-23
pubmed: 20465673
Pediatr Dermatol. 2009 May-Jun;26(3):354-6
pubmed: 19706108
Dermatol Surg. 2019 Dec;45(12):1627-1634
pubmed: 30829772
J Dermatolog Treat. 2015;26(4):347-53
pubmed: 25428573
Lasers Med Sci. 2021 Feb;36(1):165-173
pubmed: 32572662
Photomed Laser Surg. 2012 Jan;30(1):26-30
pubmed: 22054204
J Am Acad Dermatol. 2016 May;74(5):907-15
pubmed: 26785803
Lasers Surg Med. 2019 Mar;51(3):239-244
pubmed: 30681166
Int J Dermatol. 1997 May;36(5):386-8
pubmed: 9199992
Br J Dermatol. 2019 Jun;180(6):1539-1540
pubmed: 30488531
Cochrane Database Syst Rev. 2010 Jan 20;(1):CD003263
pubmed: 20091542
Indian J Dermatol Venereol Leprol. 2012 Jan-Feb;78(1):49-58
pubmed: 22199060
Aesthet Surg J. 2020 Jan 1;40(1):NP46-NP50
pubmed: 31605101
Dermatol Surg. 2001 Jun;27(6):565-8
pubmed: 11442594
J Eur Acad Dermatol Venereol. 2019 Jun;33(6):1172-1176
pubmed: 30793805
Indian J Dermatol Venereol Leprol. 2019 Jan-Feb;85(1):32-38
pubmed: 29998861
Lasers Med Sci. 2017 May;32(4):851-855
pubmed: 28265789
J Cutan Aesthet Surg. 2015 Apr-Jun;8(2):79-87
pubmed: 26157306
Dermatol Surg. 2004 Feb;30(2 Pt 1):130-5
pubmed: 14756638
J Eur Acad Dermatol Venereol. 2015 Jun;29(6):1121-7
pubmed: 25286980
J Dermatolog Treat. 2019 Nov;30(7):697-700
pubmed: 30592235
J Cutan Aesthet Surg. 2013 Apr;6(2):93-6
pubmed: 24023431
Lasers Med Sci. 2016 Sep;31(7):1343-9
pubmed: 27291387
Br J Dermatol. 2016 Apr;174(4):895-7
pubmed: 26409069
J Eur Acad Dermatol Venereol. 2011 Jul;25(7):749-57
pubmed: 21054565
Lancet. 2015 Jul 4;386(9988):74-84
pubmed: 25596811
Dermatol Surg. 2009 Apr;35(4):601-6
pubmed: 19400882
Lasers Surg Med. 2004;35(2):152-6
pubmed: 15334620
Clin Exp Dermatol. 2010 Mar;35(2):215-6
pubmed: 20447090
Lasers Med Sci. 2018 Sep;33(7):1549-1556
pubmed: 29696444
Dermatol Ther. 2019 Sep;32(5):e13052
pubmed: 31376312
J Eur Acad Dermatol Venereol. 2015 Apr;29(4):745-51
pubmed: 25352095
Br J Dermatol. 2019 Jan;180(1):193-194
pubmed: 30188576
Br J Dermatol. 2017 Nov;177(5):1293-1298
pubmed: 28403523
Br J Dermatol. 2019 Jul;181(1):210-211
pubmed: 30644997
Br J Dermatol. 2013 Dec;169(6):1246-51
pubmed: 23909405