Phase behavior and miscibility in lipid monolayers containing glycolipids.
Brewster-angle microscopy
Glycolipid-enriched domains
Grazing-incidence X-ray diffraction
Langmuir isotherm
Langmuir monolayer
Phase behaviour
Phase diagram
Phospholipid
Journal
Journal of colloid and interface science
ISSN: 1095-7103
Titre abrégé: J Colloid Interface Sci
Pays: United States
ID NLM: 0043125
Informations de publication
Date de publication:
Jun 2022
Jun 2022
Historique:
received:
27
11
2021
revised:
19
01
2022
accepted:
23
01
2022
pubmed:
18
2
2022
medline:
16
3
2022
entrez:
17
2
2022
Statut:
ppublish
Résumé
Glycolipids in biological membranes are ubiquitous and believed to be involved in the formation of ordered functional domains. However, our current knowledge about such glycolipid-enriched domains is limited because they are inherently difficult to characterize. We use grazing-incidence X-ray diffraction, isotherm measurements, and Brewster angle microscopy to investigate the phase behavior and miscibility in Langmuir lipid monolayers containing glycolipids. Glycolipid-enriched domains give rise to distinct diffraction patterns that allow for a systematic structural investigation and reveal a rich phenomenology, ranging from near-complete demixing to the formation of mixed domains with unique features. The phase behavior is governed by the headgroup chemistry and by the length and saturation of the tails.
Identifiants
pubmed: 35176545
pii: S0021-9797(22)00166-7
doi: 10.1016/j.jcis.2022.01.146
pii:
doi:
Substances chimiques
Glycolipids
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
786-796Informations de copyright
Copyright © 2022 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.