Review of Post-translational Modification of Human Serum Albumin.

Acetylation Humans Methylation Phosphorylation Protein Processing, Post-Translational Serum Albumin, Human
Human serum albumin acetylation carbonylation glycation phosphorylation post-translational modifications

Journal

Current protein & peptide science
ISSN: 1875-5550
Titre abrégé: Curr Protein Pept Sci
Pays: United Arab Emirates
ID NLM: 100960529

Informations de publication

Date de publication:
2022
Historique:
received: 08 09 2021
revised: 17 12 2021
accepted: 04 01 2022
pubmed: 19 2 2022
medline: 18 6 2022
entrez: 18 2 2022
Statut: ppublish

Résumé

Post-translational modifications (PTMs) may affect the functions of human serum albumin. Here we review reports of novel PTMs of human serum albumin. This study reviewed one hundred twenty-three recently reported novel O-phosphorylation, glycation, methylation, carbonylation, and acetylation of albumin. Furthermore, the potential impact of these PTMs on albumin functions is discussed. Knowledge of these PTMs of albumin is important for the use of albumin in medical applications, e.g., in transfusion, drug formulations, and remedies.

Identifiants

DOI: 10.2174/1389203723666220217150332 PMID: 35176988
pubmed: 35176988
pii: CPPS-EPUB-120986
doi: 10.2174/1389203723666220217150332
doi:

Substances chimiques

Serum Albumin, Human ZIF514RVZR

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

114-120

Informations de copyright

Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Auteurs

Surya Kannan (S)

College of Medicine, QU Health, Qatar University, Doha, Qatar.

Serhiy Souchelnytskyi (S)

College of Medicine, QU Health, Qatar University, Doha, Qatar.
Oranta Cancer Diagnostics AB, Uppsala, Sweden.
Lviv State University, Lviv, Ukraine.

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Classifications MeSH

questionsmedicales.fr › Métabolisme › Acylation › Acétylation › Review of Post-translational Modification of...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Review of Post-translational Modification of...
questionsmedicales.fr › Métabolisme › Alkylation › Méthylation › Review of Post-translational Modification of...
questionsmedicales.fr › Métabolisme › Phosphorylation › Review of Post-translational Modification of...
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › Modification traductionnelle des protéines › Maturation post-traductionnelle des protéines › Review of Post-translational Modification of...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines du sang › Sérumalbumine › Sérum-albumine humaine › Review of Post-translational Modification of...