Oncologic impact of concomitant prostate cancer characteristics at the time of radical cystoprostatectomy for bladder cancer: a population-based analysis.
Prostate cancer
SEER
bladder cancer
Journal
The aging male : the official journal of the International Society for the Study of the Aging Male
ISSN: 1473-0790
Titre abrégé: Aging Male
Pays: England
ID NLM: 9808210
Informations de publication
Date de publication:
Dec 2022
Dec 2022
Historique:
entrez:
18
2
2022
pubmed:
19
2
2022
medline:
22
2
2022
Statut:
ppublish
Résumé
The aim of this study was to evaluate the prognostic impact of concomitant prostate cancer (PCa) of the cancer-specific mortality (CSM) in the aging patient's papulation with bladder cancer (BCa) treated with radical cystoprostatectomy (RCP). Within the SEER database (2004-2015), 1468 patients were treated with RCP for BCa harboring histopathological PCa findings. To account for other cause mortality (OCM), multivariable competing risk regression (CRR) tested for potential BCa-CSM differences according to PCa characteristics risk factors predicting CSM. CRR analysis revealed that only following BCa characteristics, as high pathological tumor stages(Ta/Tis/T1 [REF.] vs. T2; HR 2.03, 95% CI: 1.16-3.57, Our study, based on the largest population cohort, demonstrates that even in organ-confined BCa patients, concomitant PCa as second malignancy does not represent a risk factor for survival.
Identifiants
pubmed: 35179092
doi: 10.1080/13685538.2022.2040982
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM