A series of case studies illustrating the role of flow cytometry in the diagnostic work-up of myelodysplastic syndromes.
MDS
cytopenia
dysplasia
flow cytometry
integrated diagnostics
Journal
Cytometry. Part B, Clinical cytometry
ISSN: 1552-4957
Titre abrégé: Cytometry B Clin Cytom
Pays: United States
ID NLM: 101235690
Informations de publication
Date de publication:
01 2023
01 2023
Historique:
revised:
24
01
2022
received:
01
07
2021
accepted:
10
02
2022
pubmed:
19
2
2022
medline:
19
1
2023
entrez:
18
2
2022
Statut:
ppublish
Résumé
Current guidelines recommend flow cytometric analysis as part of the diagnostic assessment of patients with cytopenia suspected for myelodysplastic syndrome. Herein we describe the complete work-up of six cases using multimodal integrated diagnostics. Flow cytometry assessments are illustrated by plots from conventional and more recent analysis tools. The cases demonstrate the added value of flow cytometry in case of hypocellular, poor quality, or ambiguous bone marrow cytomorphology. Moreover, they demonstrate how immunophenotyping results support clinical decision-making in inconclusive and clinically 'difficult' cases.
Identifiants
pubmed: 35179296
doi: 10.1002/cyto.b.22061
pmc: PMC10078764
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
87-97Informations de copyright
© 2022 The Authors. Cytometry Part B: Clinical Cytometry published by Wiley Periodicals LLC on behalf of International Clinical Cytometry Society.
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