CITY-PSO: Prescribing behaviour of French private-practice dermatologists in psoriasis management: An observational, multicentre, cross-sectional study.


Journal

Annales de dermatologie et de venereologie
ISSN: 0151-9638
Titre abrégé: Ann Dermatol Venereol
Pays: France
ID NLM: 7702013

Informations de publication

Date de publication:
Sep 2022
Historique:
received: 24 07 2021
revised: 24 10 2021
accepted: 04 01 2022
pubmed: 20 2 2022
medline: 8 9 2022
entrez: 19 2 2022
Statut: ppublish

Résumé

Information regarding the prescribing behaviour of French private-practice dermatologists (PPDs) is scarce. First, to describe the population of PPDs involved in psoriasis management. Second, to describe the population of adult patients treated for psoriasis and their management. We published a call for participation targeting PPDs; we first asked respondents to complete a form regarding their prescribing behaviour, and then to include consecutive patients consulting for psoriasis during a one-month study period and to collect patient data. The 94 participating PPDs included 1022 patients of mean age 52.9±17.9 years. The average body mass index was 28, and 25% had vascular comorbidities. Two thirds of patients had chronic psoriasis, for which 45% had consulted at least 5 times. Psoriasis was mostly with plaques (70.8%) and 11.4% of patients had psoriatic arthritis. The average body surface area (BSA) affected was 10.1%. Among the 679 patients without initial systemic treatment, 159 were started on systemic treatment. The main agents initiated were phototherapy (n=63), methotrexate (n=40), acitretin (n=30) and apremilast (n=20). In multivariate analysis, a higher BSA [Odds Ratio (OR) 1.10, 95% Confidence Interval (CI): 1.07-1.13; P<10 The main limitation of our study was that participating PPDs were strongly involved in psoriasis management, which accounts for the high proportion of moderate-to-severe psoriasis and prescription of systemic treatments. Such committed PPDs and the development of psoriasis networks are key factors for improving the quality of care provided to psoriasis patients.

Sections du résumé

BACKGROUND BACKGROUND
Information regarding the prescribing behaviour of French private-practice dermatologists (PPDs) is scarce.
OBJECTIVES OBJECTIVE
First, to describe the population of PPDs involved in psoriasis management. Second, to describe the population of adult patients treated for psoriasis and their management.
METHODS METHODS
We published a call for participation targeting PPDs; we first asked respondents to complete a form regarding their prescribing behaviour, and then to include consecutive patients consulting for psoriasis during a one-month study period and to collect patient data.
RESULTS RESULTS
The 94 participating PPDs included 1022 patients of mean age 52.9±17.9 years. The average body mass index was 28, and 25% had vascular comorbidities. Two thirds of patients had chronic psoriasis, for which 45% had consulted at least 5 times. Psoriasis was mostly with plaques (70.8%) and 11.4% of patients had psoriatic arthritis. The average body surface area (BSA) affected was 10.1%. Among the 679 patients without initial systemic treatment, 159 were started on systemic treatment. The main agents initiated were phototherapy (n=63), methotrexate (n=40), acitretin (n=30) and apremilast (n=20). In multivariate analysis, a higher BSA [Odds Ratio (OR) 1.10, 95% Confidence Interval (CI): 1.07-1.13; P<10
CONCLUSION CONCLUSIONS
The main limitation of our study was that participating PPDs were strongly involved in psoriasis management, which accounts for the high proportion of moderate-to-severe psoriasis and prescription of systemic treatments. Such committed PPDs and the development of psoriasis networks are key factors for improving the quality of care provided to psoriasis patients.

Identifiants

pubmed: 35181154
pii: S0151-9638(22)00001-1
doi: 10.1016/j.annder.2022.01.001
pii:
doi:

Substances chimiques

Acitretin LCH760E9T7

Types de publication

Journal Article Multicenter Study Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

169-175

Informations de copyright

Copyright © 2022 Elsevier Masson SAS. All rights reserved.

Auteurs

J-M Amici (JM)

Association des Dermato-Vénéréologues du Sud-Ouest (ADVSO, Association of Dermatologists and Venerologists of the French South-West), Maison de la Dermatologie, 8, rue Jules Ferry, 33290 Blanquefort, France; Dermatology department, Bordeaux university hospital, 33000 Bordeaux, France.

C Bergqvist (C)

CIC 1430 Inserm, Dermatology department, Henri-Mondor hospital, Assistance publique-Hôpitaux de Paris (AP-HP), 94000 Créteil, France.

S Ly (S)

Association des Dermato-Vénéréologues du Sud-Ouest (ADVSO, Association of Dermatologists and Venerologists of the French South-West), Maison de la Dermatologie, 8, rue Jules Ferry, 33290 Blanquefort, France; Dermatology department, Bordeaux university hospital, 33000 Bordeaux, France.

F Corgibet (F)

Fédération française de formation continue et d'évaluation en dermatologie et vénéréologie (FFFCEDV, French Federation of Continuing Education and Assessment in Dermatology), Maison de la Dermatologie, 10, cité Malesherbes, 75009 Paris, France.

J-F Seï (JF)

Fédération française de formation continue et d'évaluation en dermatologie et vénéréologie (FFFCEDV, French Federation of Continuing Education and Assessment in Dermatology), Maison de la Dermatologie, 10, cité Malesherbes, 75009 Paris, France.

J Seneschal (J)

Dermatology department, Bordeaux university hospital, 33000 Bordeaux, France.

E Sbidian (E)

CIC 1430 Inserm, Dermatology department, Henri-Mondor hospital, Assistance publique-Hôpitaux de Paris (AP-HP), 94000 Créteil, France; EpiDermE, Paris-Est Créteil university, Val-de-Marne, 94000 Créteil, France.

M Beylot-Barry (M)

Dermatology department, Bordeaux university hospital, 33000 Bordeaux, France. Electronic address: marie.beylot-barry@chu-bordeaux.fr.

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