aPDT for oral decontamination of hospitalized patients with COVID 19.
COVID-19
Oral decontamination
Photodynamic therapies
SARS-CoV-2
Journal
Photodiagnosis and photodynamic therapy
ISSN: 1873-1597
Titre abrégé: Photodiagnosis Photodyn Ther
Pays: Netherlands
ID NLM: 101226123
Informations de publication
Date de publication:
Jun 2022
Jun 2022
Historique:
received:
06
01
2022
revised:
09
02
2022
accepted:
14
02
2022
pubmed:
20
2
2022
medline:
9
6
2022
entrez:
19
2
2022
Statut:
ppublish
Résumé
Emerging variants of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) may have an impact on the virus's transmissibility and pathogenicity and an increased risk of reinfection. Antimicrobial photodynamic therapy (aPDT) is a promising technique to decontaminate the oral cavity to minimize and inactivate microorganisms' load. This article reports through a case series, a proposal for efficient oral decontamination for hospitalized patients with COVID 19 using aPDT. Samples of oral tissues were obtained after aPDT and analyzed using two methods of RT-qPCR to elucidate qualitative and quantitative viral profiles of SARS-CoV-2 RNA in the oral cavity. There was a reduction of viral load in the oral cavity immediately or one hour after the use of aPDT. This method could be a good option to decontaminate the oral cavity to minimize and inactivate microorganism load.
Identifiants
pubmed: 35181510
pii: S1572-1000(22)00051-5
doi: 10.1016/j.pdpdt.2022.102762
pmc: PMC8847072
pii:
doi:
Substances chimiques
Anti-Bacterial Agents
0
RNA, Viral
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
102762Commentaires et corrections
Type : ErratumIn
Informations de copyright
Copyright © 2022. Published by Elsevier B.V.